Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Target » Aromatase antibody

Aromatase antibody

(reset)

Principal name

Aromatase antibody

Alternative names for Aromatase antibody

Cytochrome P450 19A1, CYPXIX, Estrogen synthetase, P450AROM, CYP19A1, ARO1, CYAR, CYP19

SwissProt ID

O46512 (Horse), P11511 (Human), P19098 (Chick), P22443 (Rat), P28649 (Mouse), P46194 (Bovin)

Gene ID

1588 (CYP19A1), 13075 (Cyp19a1)

Ncbi ID

9606, NP_000094.2, NP_000094, 10116, NP_031836.1, NM_000103

Available reactivities

Bov (Bovine), Chk (Chicken), Eq (Equine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Bt (Bat), Gt (Goat), Marmoset, Mky (Monkey), Bab (Baboon), Prim (Primate)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection))

Selected product citations ‐ of SM2222P

1. Colette S, Lousse JC, Defrère S, Curaba M, Heilier JF, Van Langendonckt A, et al. Absence of aromatase protein and mRNA expression in endometriosis. Hum Reprod. 2009 Sep;24(9):2133-41. doi: 10.1093/humrep/dep199. Epub 2009 Jun 2. PubMed PMID: 19493871.
2. Bender RA, Zhou L, Wilkars W, Fester L, Lanowski JS, Paysen D, et al. Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cereb Cortex. 2010 Dec;20(12):2985-95. doi: 10.1093/cercor/bhq047. Epub 2010 Apr 26. PubMed PMID: 20421250.
3. Horling K, Santos AN, Fischer B. The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. Mol Hum Reprod. 2011 Feb;17(2):104-14. doi: 10.1093/molehr/gaq074. Epub 2010 Sep 7. PubMed PMID: 20823264.
4. Schicht M, Ernst J, Nielitz A, Fester L, Tsokos M, Guddat SS, et al. Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism. Arthritis Res Ther. 2014 Apr 11;16(2):R93. doi: 10.1186/ar4539. PubMed PMID: 24725461. 
5. Zhao, Y;Yu, Y;Zhang, Y;He, L;Qiu, L;Zhao, J;Liu, M;Zhang, J. Letrozole regulates actin cytoskeleton polymerization dynamics in a SRC-1 dependent manner in the hippocampus of mice. J. Steroid Biochem. Mol. Biol. 2016. PubMed PMID: 27866972. 
6. Fouquet, B;Santulli, P;Noel, JC;Misrahi, M. Ovarian-like differentiation in eutopic and ectopic endometrioses with aberrant FSH receptor, INSL3 and GATA4/6 expression. BBA Clin 2016, 143-152, 6. PubMed PMID: 27882303.

Background of Aromatase antibody

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450 enzymes can be classified, based on their sequence similarities, into distinct subfamilies, which include CYP1A and CYP2A. Other P450 family members include CYP19, also designated aromatase (P450arom), which catalyzes the conversion of C19 steroids to estrogens in various tissues, including placent,a gonads, adipose tissue, skin and brain. CYP19 expression is controlled by hormonally regulated promoters in different tissues and increased aromatase activity is associated with familial gynecomastia. Also, a polymorphic allele of CYP19 (repeat (TTTA)12) is present in a majority of breast cancer patients. P450 cholesterol 7α-hydroxylase, CYP7A1, is the rate limiting enzyme of bile acid synthesis in the liver, and its expression is mediated by the bile acid receptor FXR. CYP27A1 catalyzes vitamin D 25-hydroxylation and is localized to the mitochondria in kidney and liver.

General readings

1. Van Poznak CH, Hayes DF. Aromatase inhibitors for the treatment of breast cancer: is tamoxifen of historical interest only?
J Natl Cancer Inst. 2006 Sep 20;98(18):1261-3. No abstract available.
PMID: 16985239

AP00001PU-N - Aromatase
Immunohistochemical staining of human placenta using Aromatase antibody AP00001PU-N showed staining of trophoblasts (Placental Villi 40X).
AP00001PU-N - Aromatase
Immunohistochemical staining of human testis using Aromatase antibody AP00001PU-N showed staining of Leydig cells and spermatocytes in seminiferous tubules (Testis, Leydig Cells 60X).
AP00001PU-N - Aromatase
Western blot analysis of Aromatase in Human brain cell lysate using anti-Aromatase antibody AP00001PU-N.
SM2222P - Aromatase
Western blot analysis of Human placenta extract probed with anti Human Cytochrome P450 Aromatase Antibody Cat.-No SM2222P/PS (Clone H4) followed by F(ab')2 Rabbit anti Mouse IgG-HRP (Cat.-No SP1012HRP).
SM2222P - Aromatase
Staining of FFPE Human placenta with Aromatase (10x and 40x) Antibody Cat.-No SM2222PS (Clone H4) at 1/100 dilution. Antibody positive in the cell membrane of epithelial cells.
H00001588-M03 - Aromatase
Detection limit for recombinant GST tagged CYP19A1 is approximately 0.3ng/ml as a capture antibody.
PAB2868 - Aromatase
Western blot analysis of CYP19A1 polyclonal antibody ( Cat # PAB2868 ) in HL-60 cell line lysates ( 35 µg/lane ) . CYP19A1 ( arrow ) was detected using the purified polyclonal antibody ( 1 : 60 dilution ) .
PAB7447 - Aromatase
CYP19A1 polyclonal antibody ( Cat # PAB7447 ) ( 0.1 µg/ml ) staining of human placenta lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence.
AP14030PU-N - Aromatase
AP14030PU-N CYP19A1 antibody staining of HL60 cell line lysates by Western blot (35 µg/lane). CYP19A1 (arrow) was detected using the purified antibody at 1/60 dilution.
AP14221PU-N - Aromatase
AP14221PU-N CYP19A1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human placenta tissue using peroxidase-conjugate and DAB chromogen.
AP14221PU-N - Aromatase
Western blot analysis using AP14221PU-N CYP19A1 antibody in Jurkat cell line lysates (35 µg/lane). CYP19A1 (arrow) was detected using the purified antibody at 1/60 dilution.
H00001588-D01P - Aromatase
CYP19A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CYP19A1 expression in human liver.
H00001588-D01P - Aromatase
Western Blot analysis of CYP19A1 expression in transfected 293T cell line (H00001588-T02) by CYP19A1 MaxPab polyclonal antibody.Lane 1: CYP19A1 transfected lysate(57.90 KDa).Lane 2: Non-transfected lysate.
PAB12453 - Aromatase
Western blot analysis of CYP19A1 in human fetal temporal lobe lysate using CYP19A1 polyclonal antibody ( Cat # PAB12453 ). ECL exposure, 1-2 minutes.
PAB8551 - Aromatase
Western blot analysis of CYP19A1 expression in human brain tissue lysate.
AP20542PU-N - Aromatase
Immunohistochemistry analysis of CYP19A1 Antibody (Cat.-No.: AP20542PU-N) in Paraffin-Embedded Human brain tissue.
AP20542PU-N - Aromatase
Western blot (WB) analysis of CYP19A1 Antibody (Cat.-No.: AP20542PU-N) in extracts from 293 cells.
C12248-1 - Aromatase
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 19A1 Antibody. The picture on the right is treated with the synthesized peptide.
C12248-1 - Aromatase
Immunofluorescence analysis of A549 cells, using Cytochrome P450 19A1 Antibody. The picture on the right is treated with the synthesized peptide.
C12248-1 - Aromatase
Western blot analysis of extracts from 293 cells, using Cytochrome P450 19A1 Antibody. The lane on the right is treated with the synthesized peptide.
AP22508PU-N - Aromatase
Human Placenta (formalin-fixed, paraffin-embedded) stained with CYP19A1 antibody AP22508PU-N at 4 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
AP22508PU-N - Aromatase
Antibody (0.1 µg/ml) staining of Human Placenta lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA301409 - Aromatase
Detection of aromatasein human fetal temporal lobe lysate. ECL exposure, 1-2 minutes
TA302418 - Aromatase
TA302418 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA311724 - Aromatase
Western blot analysis of extracts from 293 cells, using Cytochrome P450 19A1 antibody.The lane on the right is treated with the synthesized peptide.
TA311724 - Aromatase
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Cytochrome P450 19A1 antibody.The picture on the right is treated with the synthesized peptide.
TA311724 - Aromatase
Immunofluorescence analysis of A549 cells, using Cytochrome P450 19A1 antibody.The picture on the right is treated with the synthesized peptide.
TA321053 - Aromatase
Western blot analysis of Human ovarian cancer tissue using TA321053(CYP19A1 Antibody) at dilution 1/100
TA321054 - Aromatase
Western blot analysis of Human ovarian cancer tissue using TA321054(CYP19A1 Antibody) at dilution 1/100
TA327305 - Aromatase
Western blot analysis of extracts of Jurkat cell lines, using CYP19A1 antibody.
  1. Quick-Filters:
  2. Cited (1)
  3. Overnight Delivery (1)

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aromatase antibody
Immunohistochemical staining of human placenta using Aromatase antibody AP00001PU-N showed staining of trophoblasts (Placental Villi 40X). Rabbit Purified Bov, Chk, Eq, Hu, Ms, Por, Rb, Rt, Sh P, WB
0.1 mg / €440.00
  OriGene Technologies GmbH
+2 additional images

Top Selling product!

Published recently!

Aromatase antibody
  Rabbit Polyclonal Antibody against Aromatase  
Detection of aromatasein human fetal temporal lobe lysate. ECL exposure, 1-2 minutes Rabbit IgG Purified Hu, Mky WB
0.1 ml / €450.00
  OriGene Technologies, Inc.

Aromatase antibody
  Goat Polyclonal Antibody against Aromatase / CYP19A1  
TA302418 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Aromatase antibody
  Rabbit polyclonal Cytochrome P450 19A1 antibody  
Western blot analysis of extracts from 293 cells, using Cytochrome P450 19A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

Aromatase antibody
  Anti-ARO Rabbit Polyclonal Antibody  
Western blot analysis of Human ovarian cancer tissue using TA321053(CYP19A1 Antibody) at dilution 1/100 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Aromatase antibody
  Anti-ARO Rabbit Polyclonal Antibody  
Western blot analysis of Human ovarian cancer tissue using TA321054(CYP19A1 Antibody) at dilution 1/100 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Aromatase antibody
  Rabbit anti-CYP19A1 Polyclonal Antibody  
Western blot analysis of extracts of Jurkat cell lines, using CYP19A1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Aromatase (Center) antibody
Western blot analysis of anti-CYP19A1(Center) Pab (Cat.#AP14030PU-N) in HL60 cell line lysates (35ug/lane). CYP19A1(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Aromatase (C-term) antibody
AP14221PU-N CYP19A1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human placenta tissue using peroxidase-conjugate and DAB chromogen. Rabbit Ig Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Aromatase antibody
Immunohistochemistry analysis of CYP19A1 Antibody (Cat.-No.: AP20542PU-N) in Paraffin-Embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

Aromatase (475-486) antibody
Human Placenta (formalin-fixed, paraffin-embedded) stained with CYP19A1 antibody AP22508PU-N at 4 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Hu E, P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

CRISPR

Catalog No. Species Donor Vector  

CYP19A1 - human gene knockout kit via CRISPR
CYP19A1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR
CYP19A1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR
CYP19A1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP19A1 - human gene knockout kit via CRISPR
CYP19A1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

15 Item(s)

per page
15 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (4)
  2. Primary Antibody (11)
Clonality
  1. Polyclonal (11)
Target
  1. Aromatase (11)
Property
  1. 475-486 (1)
  2. C-term (1)
  3. Center (1)
Reactivity
  1. Human (Hu) (11)
  2. Mouse (Ms) (6)
  3. Rat (Rt) (6)
  4. Bovine (Bov) (1)
  5. Chicken (Chk) (1)
  6. Equine (Eq) (1)
  7. Monkey (Mky) (1)
  8. Porcine (Por) (1)
  9. Rabbit (Rb) (1)
  10. Sheep (Sh) (1)
Applications
  1. Western blot / Immunoblot (WB) (11)
  2. Paraffin Sections (P) (6)
  3. Enzyme Immunoassay (E) (4)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
Presentation
  1. Purified (8)
  2. Aff - Purified (3)
Host
  1. Rabbit (9)
  2. Goat (2)
Images
  1. 1 image (11)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (11)
  2. Paraffin Sections (P) (4)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. OriGene Technologies (15)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn