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ATF6 beta antibody

Principal name

ATF6 beta antibody

Alternative names for ATF6 beta antibody

ATF-6, CREBL1, G13, Creb-rp, Activating transcription factor 6 beta, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, cAMP response element-binding protein-related protein, Protein G13

SwissProt ID

O35451 (Mouse), Q99941 (Human)

Gene ID

1388 (ATF6B), 12915 (Atf6b)

Ncbi ID

NP_004372, 9606, NP_001129625.1, NP_059102.1, NM_001136153

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of ATF6 beta antibody

ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Speek,M., et al., (1996) Hum. Mol. Genet. 5 (11), 1749-1758

Human HepG2; WB Suggested Anti-CREBL1 Antibody Titration: 1.0ug/ml. Positive Control: HepG2 cell lysate; CREBL1 antibody - N-terminal region (ARP32167_T100) in Human HepG2 cells using Western Blot

ARP32167_T100

Western blot (WB) analysis of ATF6B antibody (Cat.-No.: AP06751PU-N) at 1/500 dilution
Lane1:MCF-7 whole cell lysate
Lane2:Mouse liver tissue lysate
Lane3:Rat liver tissue lysate

AP06751PU-N

Detection limit for recombinant GST tagged CREBL1 is approximately 1ng/ml as a capture antibody.

H00001388-M02

Human Muscle; WB Suggested Anti-CREBL1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Muscle; CREBL1 antibody - middle region (ARP31562_P050) in Human Muscle cells using Western Blot

ARP31562_P050

Western blot analysis of extracts from COLO205 cells, using ATF6B Antibody. The lane on the right is treated with the synthesized peptide.

Western blot analysis of ATF6B expression in HepG2 (A); mouse liver (B); rat liver (C) whole cell lysates.

Western blot analysis of extracts from COLO205 cells, using ATF6B antibody.The lane on the right is treated with the synthesized peptide.

TA313692

WB Suggested Anti-CREBL1 Antibody Titration: 1.0ug/ml; Positive Control: HepG2 cell lysate

TA330184

Western blot analysis on COLO205 cell lysate using ATF6B Antibody

TA347605

WB Suggested Anti-CREBL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle

TA329335

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA313692	ATF6 beta antibody
	Rabbit polyclonal anti-ATF6B antibody
	Rabbit	IgG	Purified	Hu	E, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
TA347605	ATF6 beta antibody
	Rabbit Polyclonal Anti-ATF6B Antibody
	Rabbit	IgG	Purified	Hu	WB	0.1 mg / €335.00
						OriGene Technologies, Inc.
AP06751PU-N	ATF6 beta antibody
	Rabbit		Aff - Purified	Hu	WB	0.1 mg / €370.00
						OriGene Technologies GmbH

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