Beclin-1 antibody
Principal name
Beclin-1 antibody
Alternative names for Beclin-1 antibody
BECN1, GT197, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197
SwissProt ID
O88597 (Mouse), Q14457 (Human), Q4A1L4 (Bovin), Q4A1L5 (Pig), Q5ZKS6 (Chick), Q91XJ1 (Rat)
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F)
Background of Beclin-1 antibody
Bellini-1 (beclin 1, autophagy related) is a protein that in humans is encoded by the BECN1 gene, also known as BECN1, ATG6, VPS30, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. Human beclin encodes a novel 450-amino acid protein containing a coiled-coil region, within which it has limited homology to myosin-like proteins. Northern blot analysis of mouse and adult human tissues revealed widespread beclin expression. A 2.2-kb transcript was present at highest levels in human skeletal muscle and at detectable levels in all tissues examined. In some tissues, additional 1.7- and 1.4-kb transcripts were observed, suggesting the presence of alternatively spliced transcripts. Immunoperoxidase staining of human hippocampus and frontal cortex sections revealed beclin immunoreactivity in many neurons throughout these regions, as well as in some glial cells. Beclin protects against infection by a neurovirulent strain of Sindbis virus that is known to overcome the protective effects of Bcl2. Liang et al. showed that beclin reduced Sindbis virus replication in mouse brain and reduced Sindbis virus-induced cell death in mouse brain.
General readings
1. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.
Tsao T-S, Lodish HF, and Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Euro. J. Pharmacol. 2002; 440:213-21.
2. Wong GW, Wang J, Hug C, et al. A family of Acrp30/ adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.
3. Shapiro L and Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr. Biol. 1998; 8:335-8.

























































































- Quick-Filters:
- Cited (1)
- Highly Validated (13)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA502617 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI4A10 (formerly 4A10) | |||||||
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Mouse | IgG2a | OTI4A10 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
Top Selling product! |
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| TA301470 | Beclin-1 antibody |
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| Rabbit Polyclonal Antibody against Beclin 1 | |||||||
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Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 ml /
€475.00
|
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA336561 | Beclin-1 antibody |
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| Rabbit Polyclonal Beclin 1/ATG6 Antibody | |||||||
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Rabbit | Purified | Can, Hu, Ms, Por, Prim | C, ICC/IF, P, WB |
50 µl /
€475.00
|
||
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA502517 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI3H8 (formerly 3H8) | |||||||
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Mouse | IgG2a | OTI3H8 | Purified | Hu, Mky, Rt | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+7 additional images |
Highly validated antibody! |
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| TA502527 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI3F3 (formerly 3F3) | |||||||
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Mouse | IgG1 | OTI3F3 | Purified | Hu, Mky, Rt | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+5 additional images |
Highly validated antibody! |
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| TA502615 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5) | |||||||
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Mouse | IgG2a | OTI2C5 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA502616 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI3C3 (formerly 3C3) | |||||||
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Mouse | IgG1 | OTI3C3 | Purified | Can, Hu, Mky, Rt | F, ICC/IF, P, WB |
0.1 ml /
€379.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA502618 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) | |||||||
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Mouse | IgG2a | OTI2D4 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA502619 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) | |||||||
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Mouse | IgG1 | OTI2A7 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA502643 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI1F1 (formerly 1F1) | |||||||
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Mouse | IgG2a | OTI1F1 | Purified | Can, Hu, Rt | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+6 additional images |
Highly validated antibody! |
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| TA502674 | Beclin-1 antibody |
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| BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI1E1 (formerly 1E1) | |||||||
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Mouse | IgG1 | OTI1E1 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| AM06595SU-N | Beclin-1 antibody |
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Mouse | IgG1 | 2A4 | Ascites | Hu | E, F, P, WB |
0.1 ml /
€410.00
|
| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| AP22863PU-N | Beclin-1 (C-term) antibody |
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Rabbit | Purified | Hu, Ms | E, ICC/IF, P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
+4 additional images |
Highly validated antibody! |
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| AP22864PU-N | Beclin-1 (N-term) antibody |
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![]() |
Rabbit | Purified | Hu, Ms, Rt | E, P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| TA301471 | Beclin-1 antibody |
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| Rabbit Polyclonal Antibody against Beclin 1 | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 ml /
€395.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA306255 | Beclin-1 (C-term) antibody |
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| Rabbit Polyclonal Beclin-1 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu, Ms | E, ICC/IF, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA306256 | Beclin-1 (N-term) antibody |
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| Rabbit Polyclonal Beclin-1 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA321594 | Beclin-1 antibody |
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| Anti-BECN1 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA321595 | Beclin-1 antibody |
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| Anti-BECN1 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA336697 | Beclin-1 antibody |
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| Mouse Monoclonal Beclin 1/ATG6 Antibody (4H10) | |||||||
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Mouse | IgG1 | 4H10 | Purified | Hu | C, P, WB |
0.1 ml /
€415.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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+2 additional images

![Western Blot: Beclin 1 Antibody [TA336561] - Beclin 1 antibody image from verified customer review.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB110-87318-1-W.jpg)
















![Western Blot: Beclin 1 Antibody (4H10) [TA336697] - Analysis of Beclin 1 in 1. NIH3T3 cell lysate and 2. Cos7 cell lysate.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP1-00085-1-W.jpg)