Beta-2-microglobulin antibody
Principal name
Beta-2-microglobulin antibody
Alternative names for Beta-2-microglobulin antibody
B2M, Beta-2 microglobulin, Beta 2 microglobulin
SwissProt ID
P01887 (Mouse), P01888 (Bovin), P07151 (Rat), P21611 (Chick), P61769 (Human), Q07717 (Pig)
Ncbi ID
NP_004039.1, NP_036644.1, 9606, 9031, NP_004039, NP_036644, NM_004048, NM_012512
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P), Immunoelectron Microscopy (EM), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), EPair for Elisa (EPair)
Background of Beta-2-microglobulin antibody
ß2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a terry membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system. As an integral component of the MHC class I complex,ß2-microglobulin plays a critically important role in immune system function. It has important relevance to cancer biology research; for example, research studies have shown that nearly one-third of diffuse large B cell lymphomas contain mutations that ictivate ß2-microglobulin gene function, thereby allowing tumor cells to escape immune detection. In additon,ß2-microglobulin has been identified as an amyloid preprotein with collagen-binding affinity; its accumulation in osteoarthritic lesions of long-term dialysis patients is reportedly a contributing factor to the condition known as amyloid osteoarthropathy.
General readings
1. Hilgert I, Horejsi V, Kristofova H.: The use of murine monoclonal antibody B2M-01 for
detection and purification of human beta 2-microglobulin. Folia Biol (Praha). 1984;30(6):369-76.
2. Drbal K, Angelisova P, Hilgert I, Cerny J, Novak P, Horejsi V.: A proteolytically truncated
form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated
myeloid cells. Blood. 2001 Sep 1;98(5):1561-6.



Lane 1: RAJI human Burkitt lymphoma cell line
Lane 2: EL4 mouse lymphoblastic lymphoma cell line
Lane 3: U937 human histiocytic lymphoma cell line



Lane 1: RAJI human Burkitt lymphoma cell line
Lane 2: EL4 mouse lymphoblastic lymphoma cell line
Lane 3: U937 human histiocytic lymphoma cell line









































































- Quick-Filters:
- Cited (2)
- Highly Validated (3)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| BM604B | Beta-2-microglobulin antibody |
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Mouse | IgG2a | B2M-01 | Biotin | Hu | F |
0.1 mg /
€260.00
|
| OriGene Technologies GmbH | |||||||
+2 additional images |
Published recently! |
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| BM604HRP | Beta-2-microglobulin antibody |
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Mouse | IgG2a | B2M-01 | HRP | Hu | E, WB |
0.1 mg /
€280.00
|
| OriGene Technologies GmbH | |||||||
+2 additional images |
Published recently! |
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| TA327075 | Beta-2-microglobulin antibody |
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| Rabbit anti-B2M Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA802776 | Beta-2-microglobulin antibody |
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| B2M mouse monoclonal antibody, clone OTI1A9 (formerly 1A9) | |||||||
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Mouse | IgG1 | OTI1A9 | Purified | Hu | E, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| BM604S | Beta-2-microglobulin antibody |
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Mouse | IgG2a | B2M-01 | Purified | Hu | E, F, ICC/IF, IP, P, R, WB |
0.1 mg /
€210.00
|
| OriGene Technologies GmbH | |||||||
+4 additional images |
Highly validated antibody! |
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| AP31992PU-N | Beta-2-microglobulin (65-79) antibody |
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Goat | Aff - Purified | Bov, Hu | E, WB |
0.1 mg /
€380.00
|
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| OriGene Technologies GmbH | |||||||
OriGene recommends this product for Western blotting. |
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| TA311281 | Beta-2-microglobulin (N-term) antibody |
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| Goat Anti-beta-2-microglobulin (B2M) Antibody | |||||||
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Goat | Aff - Purified | Bov, Hu | E, WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
| TA318002 | Beta-2-microglobulin antibody |
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| B2M / Beta 2 Microglobulin Mouse Monoclonal (2213) Antibody | |||||||
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Mouse | IgG1 | 2213 | Purified | Hu | E |
50 µl /
€425.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA319173 | Beta-2-microglobulin antibody |
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| Rabbit polyclonal Beta-2-Microglobulin antibody | |||||||
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Rabbit | Purified | Hu | C, E, ICC/IF, P, WB |
0.1 mg /
€515.00
|
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| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA319617 | Beta-2-microglobulin antibody |
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| Rabbit Polyclonal B2M Antibody | |||||||
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Rabbit | IgG | Purified | Hu | WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA321615 | Beta-2-microglobulin antibody |
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| Anti-B2M Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA321616 | Beta-2-microglobulin antibody |
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| Anti-B2M rabbit polyclonal antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA803617 | Beta-2-microglobulin antibody |
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| B2M mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) | |||||||
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Mouse | IgG1 | OTI1A7 | Purified | Hu | E, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| AM02302PU-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | D6E4 | Aff - Purified | Hu | E, ICC/IF |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM02303PU-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | D2E9 | Aff - Purified | Hu | E, E(capture), F, ICC/IF, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
+2 additional images |
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| AM08132BT-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | F21-21 | Biotin | Chk, Tr | F |
0.5 mg /
€450.00
|
| OriGene Technologies GmbH | |||||||
| AM08132FC-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | F21-21 | FITC | Chk, Tr | F |
0.5 mg /
€500.00
|
| OriGene Technologies GmbH | |||||||
| AM08132PU-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | F21-21 | Purified | Chk, Tr | C, F, IP, WB |
0.5 mg /
€370.00
|
| OriGene Technologies GmbH | |||||||
| AM08132RP-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | F21-21 | PE | Chk, Tr | F |
0.1 mg /
€340.00
|
| OriGene Technologies GmbH | |||||||
| AM09263PU-N | Beta-2-microglobulin antibody |
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Mouse | IgG1 | D6D1 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||

















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