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BMP4 antibody

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Principal name

BMP4 antibody

Alternative names for BMP4 antibody

BMP2B, BMP-2B, BMP-4, DVR4, Bone morphogenetic protein 4

SwissProt ID

P12644 (Human), P21275 (Mouse), Q06826 (Rat), Q2KJH1 (Bovin)

Gene ID

652 (BMP4), 12159 (Bmp4)

Ncbi ID

NP_001193.2, 9606, NP_001193, 10090, NP_001193.1, NP_031580.2, NP_031580, NM_007554, NM_001202, NM_130850

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Frog, Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Rb (Rabbit), Bt (Bat), Can (Canine), Eq (Equine), Fi (Fish), Gt (Goat), Hst (Hamster), Mky (Monkey), Op (Opossum), Prim (Primate), Sh (Sheep), Xen (Xenopus), Shrew, Bear

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Dot blot (Dot), Flow Cytometry (F)

Background of BMP4 antibody

The Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily of cytokines that are involved in development, differentiation, and disease. T he transforming growth factor-beta (TGF-beta) super-family consists of a large number of growth and differentiation factors, such as TGF-betas, activins, inhibins, growth and differentiation factors (GDFs), and bone morphogenetic proteins (BMPs). These TGF beta ligands act through specific serine/threonine type I and Type II receptor kinases (1). These type I and II receptor kinases subsequently activate Smad proteins, which then propagate the signals into the nucleus to regulate target gene expression. Several BMP isotypes have been identified (BMP1 through BMP16) have been recovered through molecular cloning. Recombinant protein products from several of these clones (BMP2-BMP16) are members of the TGF-beta super-family of regulatory ligands. There exist high degree of amino acid sequence homology between BMP5, BMP6, and BMP7, that constitute a subfamily within the BMPs. The signaling systems of BMP are highly conserved from flies to mammals and have been shown to be important in the development of multiple organs.
The formation of skeleton requires a highly regulated inductive signals with antagonist negative feed back system. Inappropriate or excessive expression of BMPs (bone morphogenetic proteins) or their antagonists (Noggin, ectodin) results in genetic disorders affecting the skeleton, such as fibrodysplasia ossificans progressiva. BMP signaling mediated through binding to its receptors is a critical step in the induction of abnormal ossification. BMP-4 expression has been shown in the developmental bone formation in the alveolar bone of rat embryo by immunohistochemistry (2). The bone morphogenetic proteins (BMP) are implicated in several inductive differentiation processes in vertebrate ontogeny and patterning of nervous system. BMP4 and its antagonist Noggin play important role in the CNS development, the expression of BMP4 in rat hippocampus increase gradually and reached its highest levels during weaning and then decline slightly there after (3). BMP4 is also required in normal development of mouse inner ear (3).

General readings

Moon BS., et al. (2009) Exp Mol Med. 41(2):116-25.
Li BC., et al. (2009) J Trauma. 66(2):450-6.

AM01363PU-N - BMP4
Immunofluorescence staining of HepG2 cells using BMP4 antibody Cat.-No AM01363PU-N. The primary antibody was incubated at 3.0 µg/ml overnight at 4˚C followed by a fluorescent labeled secondary antibody. Information and photo are courtesy of the Cell Profiling group, SciLifeLab Stockholm.
AP07891PU-N - BMP4
Figure 1. Staining BMP4 in Lung, Respiratory Epithelium by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue.
PAB3673 - BMP4
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with BMP4 polyclonal antibody ( Cat # PAB3673 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
AR09132PU-L - BMP4
AR09132PU-L - BMP4
Recombinant human BMP-4, aa 293 - 408: 15% SDS-PAGE (3 µg)
PAB9481 - BMP4
Western blot analysis of BMP4 polyclonal antibody using recombinant human BMP4.
AP22623PU-N - BMP4
Human Colon (formalin-fixed, paraffin-embedded) stained with BMP4 antibody AP22623PU-N at 1/100 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
AP22650PU-N - BMP4
Formalin-Fixed, Paraffin-Embedded Human Kidney stained with BMP4 antibody Cat.-No AP22650PU-N at 5 µg/ml after heat-induced antigen retrieval.
AP22650PU-N - BMP4
Formalin-Fixed, Paraffin-Embedded Human Lung stained with BMP4 antibody Cat.-No AP22650PU-N at 5 µg/ml after heat-induced antigen retrieval.
AP22650PU-N - BMP4
Formalin-Fixed, Paraffin-Embedded Human Placenta stained with BMP4 antibody Cat.-No AP22650PU-N at 5 µg/ml after heat-induced antigen retrieval.
AM06396SU-N - BMP4
Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate.
MAB-005 - BMP4
MAB-005 - BMP4
MAB-005 - BMP4
MAB-005 - BMP4
PRO-50004-0100 - BMP4
Human BMP4 (Bone morphogenetic protein 4) recombinant protein
PRO-50004-0050 - BMP4
Human BMP4 (Bone morphogenetic protein 4) recombinant protein
PRO-50004-0020 - BMP4
Human BMP4 (Bone morphogenetic protein 4) recombinant protein
CEK1024 - Human BMP4 ELISA Kit
Representative Standard Curve
TA500014 - BMP4
TA500014 - BMP4
TA500014 - BMP4
Anti-BMP4 mouse monoclonal antibody (TA500014) immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY BMP4(RC219979)
TA500014 - BMP4
BMP4 antibody ( 6B7 ) at 1:100000 dilution + Recombinant human BMP4 (Cat# RC219979)
UM500038 - BMP4
UM500038 - BMP4
UM500038 - BMP4
Immunohistochemical staining of paraffin-embedded human melanoma using anti-BMP4 mouse monoclonal antibody; an unrelated antibody of the same isotype was used as negative control. (Clone UMAB38 , dilution 1:50; heat-induced epitope retrieval by 10mM citri
UM500038 - BMP4
UM500038 - BMP4
UM500038 - BMP4
HEK293T cells transfected pCMV6-ENTRY BTRC (RC219979, Left lane) cDNA for 48 hrs or HEK293T cells untransfected (Right lane) were lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BTRC.
UM500038 - BMP4
Western Blot analysis of 10 different human tissue lysates (10ug) by using anti-BMP4 monoclonal antibody (clone UMAB42, 1:500)
UM500038 - BMP4
UM500038 - BMP4
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-BMP4 mouse monoclonal antibody (Clone UMAB38). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-BMP4 (Clone UMAB38) very specifically recognizes BMP4 antigen on OriGene protein microarray chip.
TP723042 - BMP4
TP723043 - BMP4
TP723044 - BMP4
TA323208 - BMP4
Predicted band size: 47 kDa . Positive control: Human lymphoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds)
TA323209 - BMP4
Predicted band size: 47 kDa . Positive control: Mouse intestinumm tenue tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lysate: 50 ug Primary antibody: 1/450 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 minutes)
TA323209 - BMP4
Predicted cell location: Cytoplasm. Positive control: Human brain tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using BMP4 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200)
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BMP4 antibody
  BMP4 mouse monoclonal antibody,clone UMAB42  
BMP4 Mouse IgG1 UMAB42 Purified Hu
0.1 ml / €468.00
  OriGene Technologies, Inc.
+8 additional images

Highly validated antibody!

UltraMAB

BMP4 antibody
  BMP4 mouse monoclonal antibody,clone UMAB42  
BMP4 Mouse IgG1 UMAB42 Purified Hu
30 µl / €180.00
  OriGene Technologies, Inc.
+8 additional images

Highly validated antibody!

UltraMAB

BMP4 antibody
  anti-BMP4 mouse monoclonal antibody, clone OTI6B7 (formerly 6B7)  
BMP4 Mouse IgG1 OTI6B7 Purified Hu ICC/IF, P, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

TrueMAB

BMP4 antibody
  Anti-BMP4 Rabbit Polyclonal Antibody  
Predicted band size: 47 kDa . Positive control: Human lymphoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

BMP4 antibody
  Anti-BMP4 Rabbit Polyclonal Antibody  
Predicted band size: 47 kDa . Positive control: Mouse intestinumm tenue tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lysate: 50 ug Primary antibody: 1/450 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

BMP4 antibody
Immunofluorescence staining of HepG2 cells using BMP4 antibody Cat.-No AM01363PU-N. The primary antibody was incubated at 3.0 µg/ml overnight at 4˚C followed by a fluorescent labeled secondary antibody. Information and photo are courtesy of the Cell Profiling group, SciLifeLab Stockholm. Mouse IgG2b Azide Free Hu E, FN, ICC/IF, WB
0.5 mg / €220.00
  OriGene Technologies GmbH

BMP4 antibody
Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate. Mouse IgG1 10F4B4 Ascites Hu E, WB
0.1 ml / €380.00
  OriGene Technologies GmbH

BMP4 (20-34) antibody
Figure 1. Staining BMP4 in Lung, Respiratory Epithelium by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu E, P
50 µg / €425.00
  OriGene Technologies GmbH

BMP4 antibody
Human Colon (formalin-fixed, paraffin-embedded) stained with BMP4 antibody AP22623PU-N at 1/100 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit IgG Purified Bov, Bt, Can, Chk, Elephant, Eq, Gt, Hst, Hu, Mky, Ms, Por, Rb, Rt, Xen P, WB
50 µl / €425.00
  OriGene Technologies GmbH

BMP4 antibody
Formalin-Fixed, Paraffin-Embedded Human Kidney stained with BMP4 antibody Cat.-No AP22650PU-N at 5 µg/ml after heat-induced antigen retrieval. Rabbit Aff - Purified Chk, Hu, Ms, Rb, Rt P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+2 additional images

BMP4 (20-34) antibody
BMP4 staining of Human Lung Tissue, respiratory epithelium: Formalin-Fixed Paraffin-Embedded (FFPE). Rabbit IgG Aff - Purified Bov, Chk, Frog, Hu, Ms, Por, Rt, Ze P
50 µg / €530.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BMP4 (transcript variant 1)
  Purified recombinant protein of Human bone morphogenetic protein 4 (BMP4), transcript variant 1.  
BMP4 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
10 µg / €230.00
  OriGene Technologies, Inc.
 

BMP4
  Purified recombinant protein of Mouse bone morphogenetic protein 4 (Bmp4).  
BMP4 Mouse > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
10 µg / €230.00
  OriGene Technologies, Inc.
 

BMP4
BMP4 Human Purified > 95 % E. coli
10 µg / €530.00
  Neuromics Antibodies

BMP4 (Carrier Free)
BMP4 Human Purified > 95 % NSO cells
10 µg / €530.00
  Neuromics Antibodies

BMP4
BMP4 Human Purified > 95 % E. coli
2 µg / €190.00
  Neuromics Antibodies

BMP4
BMP4 Human Purified > 95 % E. coli
10 µg / €290.00
  Neuromics Antibodies

17 Item(s)

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17 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Primary Antibody (11)
  2. Protein | Growth Factor (6)
Clonality
  1. Polyclonal (6)
  2. Monoclonal (5)
Target
  1. BMP4 (17)
Property
  1. 20-34 (2)
Reactivity
  1. Human (Hu) (11)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (5)
  4. Chicken (Chk) (3)
  5. Bovine (Bov) (2)
  6. Porcine (Por) (2)
  7. Rabbit (Rb) (2)
  8. Bat (Bt) (1)
  9. Canine (Can) (1)
  10. Elephant (1)
  11. Equine (Eq) (1)
  12. Frog (1)
  13. Goat (Gt) (1)
  14. Hamster (Hst) (1)
  15. Monkey (Mky) (1)
  16. Xenopus (Xen) (1)
  17. Zebrafish (Ze) (1)
Applications
  1. Western blot / Immunoblot (WB) (7)
  2. Paraffin Sections (P) (6)
  3. Enzyme Immunoassay (E) (5)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  5. Functional assay (FN) (1)
Presentation
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  2. Aff - Purified (2)
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Host
  1. Rabbit (6)
  2. Mouse (5)
Images
  1. 1 image (15)
  2. 3+ images (4)
  3. 5+ images (2)
Images: Applications
  1. Paraffin Sections (P) (6)
  2. Western blot / Immunoblot (WB) (6)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. IHC (1)
Species (Protein)
  1. Human (5)
  2. Mouse (1)
Source
  1. E. coli (5)
  2. NSO cells (1)
Manufacturer
  1. OriGene Technologies (12)
  2. Neuromics Antibodies (5)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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