BMPR2 antibody
Principal name
BMPR2 antibody
Alternative names for BMPR2 antibody
BMP type II receptor, BMPR-II, PPH1, Bone morphogenetic protein receptor type-2, Bone morphogenetic protein receptor type II
Ncbi ID
9606, NP_001195.2, NM_001204, NP_001195, NP_031587.1, NM_007561
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of BMPR2 antibody
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq)
Western blot analysis of BMPR2 polyclonal antibody ( Cat # PAB1907 ) in mouse heart tissue lysate. BMPR2 ( arrow ) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Detection limit for recombinant GST tagged BMPR2 is approximately 3ng/ml as a capture antibody.
Figure 2. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BMPR2 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Figure 1. Western blot analysis of anti-BMPR2 Pab (Cat#AP11864PU-N) in mouse heart tissue lysate. BMPR2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Western Blot analysis of BMPR2 expression in transfected 293T cell line (H00000659-T02) by BMPR2 MaxPab polyclonal antibody.Lane 1: BMPR2 transfected lysate(115.20 KDa).Lane 2: Non-transfected lysate.
Immunohistochemical analysis of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) using BMPR2 antibody Cat.-No AM06596SU-N with DAB staining.
Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and tonsil tissues (right) using BMPR2 antibody Cat.-No AM06596SU-N with DAB staining.
Western blot analysis using BMPR2 antibody Cat.-No AM06596SU-N against Hela (Lane 1), A431 (Lane 2), NIH/3T3 (Lane 3), Cos7 (Lane 4) and PC-12 (Lane 5) cell lysate.
Immunohistochemical analysis of paraffin-embedded muscle tissues (left) and kidney cancer tissues (right) using BMPR2 antibody Cat.-No AM06597SU-N with DAB staining.
Immunofluorescence analysis of Eca109 cells using BMPR2 antibody Cat.-No AM06597SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Western blot analysis using BMPR2 antibody Cat.-No AM06597SU-N against Hela (Lane 1), A431 (Lane 2), NIH/3T3 (Lane 3), Cos7 (Lane 4) and PC-12 (Lane 5) cell lysate.
Western blot analysis of BMPR2 expression in HEK293T (A); Raw264.7 (B) whole cell lysates.
Sample(30 ug of whole cell lysate). A:H1299. B:Raji . 7.5% SDS PAGE. TA308587 diluted at 1:1000
Sample (30 ug of whole cell lysate). . A:NIH-3T3. 7.5% SDS PAGE. . TA308587 diluted at 1:1000.
Predicted cell location: Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using BMPR2 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x200)
Predicted cell location: Cytoplasm,Nucleus. Positive control: Human brain and liver cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using BMPR2 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x 200)
Predicted cell location: Cytoplasm,Nucleus. Positive control: Human brain and liver cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using BMPR2 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x200)
TA329090 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western blot analysis of extracts of various cell lines, using BMPR2 antibody.
Western blot analysis of BMPR2 expression in H1299 whole cell lysate
- Quick-Filters:
- Highly Validated (2)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM06596SU-N | BMPR2 antibody |
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Mouse | IgG1 | 1F12 | Ascites | Hu, Mky, Ms, Rt | E, P, WB |
0.1 ml /
€410.00
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| OriGene Technologies GmbH | |||||||
 +3 additional images |
Highly validated antibody! |
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| AM06597SU-N | BMPR2 antibody |
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Mouse | IgG1 | 3F6 | Ascites | Hu, Mky, Ms, Rt | E, ICC/IF, P, WB |
0.1 ml /
€410.00
|
| OriGene Technologies GmbH | |||||||
| +3 additional images |
Highly validated antibody! |
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| TA308587 | BMPR2 antibody |
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| Rabbit polyclonal antibody to BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)) | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms | WB |
0.1 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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| TA323210 | BMPR2 antibody |
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| Anti-BMPR2 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA323211 | BMPR2 antibody |
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| Anti-BMPR2 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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| TA329090 | BMPR2 antibody |
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| BMPR2 Goat Polyclonal Antibody | |||||||
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Goat | Aff - Purified | Bov, Can, Hu, Ms, Rt | E, WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
| TA332828 | BMPR2 antibody |
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| Rabbit anti-BMPR2 Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
| TA348001 | BMPR2 antibody |
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| Rabbit Polyclonal Anti-BMPR2 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
| AP11864PU-N | BMPR2 (N-term) antibody |
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Rabbit | Ig | Purified | Hu, Ms | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| +1 additional image |
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CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN208673 | BMPR2 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN208673BN | BMPR2 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN208673LP | BMPR2 - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN208673RB | BMPR2 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP308673 | BMPR2 |
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| Recombinant protein of human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€788.00
|
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| OriGene Technologies, Inc. | |||||
| TP720623 | BMPR2 |
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| Purified recombinant protein of Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2) | |||||
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Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
50 µg /
€299.00
|
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| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY420077 | BMPR2 overexpression lysate |
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0.1 mg /
€295.00
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|
| OriGene Technologies, Inc. |