Bystin antibody

Principal name

Bystin antibody

Alternative names for Bystin antibody

BYSL

SwissProt ID

O54825 (Mouse), Q13895 (Human), Q5E9N0 (Bovin), Q80WL2 (Rat)

Gene ID

705 (BYSL), 53414 (Bysl), 359727

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of Bystin antibody

Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregncy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bystin antibody

  Rabbit Polyclonal BYSL Antibody  
ELISA: BYSL Antibody Rabbit IgG Purified Hu E
50 µg / €409.00
  OriGene Technologies, Inc.

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