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CACNG2 antibody

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Principal name

CACNG2 antibody

Alternative names for CACNG2 antibody

TARP gamma-2, Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Transmembrane AMPAR regulatory protein gamma-2

SwissProt ID

O88602 (Mouse), Q71RJ2 (Rat), Q9Y698 (Human)

Gene ID

10369 (CACNG2), 12300 (Cacng2)

Ncbi ID

NP_006069.1, 9606, 10116, NP_006069, NP_031609.1, NM_006078

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CACNG2 antibody

Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits alpha1, alpha2/delta, beta in a 1:1:1 stoichiometry. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the alpha1 subunits contain the ion channel pore while the auxiliary alpha2/delta and beta subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the alpha1, alpha2/delta, beta core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed gamma 1. Upon co-expression with the alpha1.1, alpha2/delta1, beta1a subunits of the skeletal muscle VDCC, gamma subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel2. Together, these results suggest that gamma subunits modulate skeletal muscle VDCCs by stabilising their conformation. The gamma 2 subunits, or stargazin, the product of a gene mutated in the stargazer mouse, is a homolog of the gamma 1 channel and is selectively expressed in the brain. It is considered to be a putative neuronal Ca2+ channel subtype mainly based on its homology to the gamma 1.

AP05141PU-N - CACNG2
Western blot analysis using gamma2 antibody on rat brain lysate.
H00010369-B01P - CACNG2
Western Blot analysis of CACNG2 expression in transfected 293T cell line (H00010369-T02) by CACNG2 MaxPab polyclonal antibody.Lane 1: CACNG2 transfected lysate(35.53 KDa).Lane 2: Non-transfected lysate.
PAB9618 - CACNG2
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k Cacng2 protein. Using Cacng2 polyclonal antibody ( Cat # PAB9618 ).
PAB9884 - CACNG2
Western blot analysis using Cacng2 polyclonal antibody on rat brain lysate.
ARP35189_P050 - CACNG2
Rat Liver; WB Suggested Anti-Cacng2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Rat Liver; Cacng2 antibody - middle region (ARP35189_P050) in Rat Liver cells using Western Blot
75-252 - CACNG2/4/8
Adult rat brain membrane immunoblot
75-252 - CACNG2/4/8
Middle: transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged TARPGamma2/3/4/8 or untagged Kv2.1 plasmid and probed with N245/36 (left) and N86/8 (right) TC supe.
73-252 - CACNG2/4/8
Adult rat brain membrane immunoblot
73-252 - CACNG2/4/8
Middle: transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged TARPGamma2/3/4/8 or untagged Kv2.1 plasmid and probed with N245/36 (left) and N86/8 (right) TC supe.
75-242 - CACNG2
Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University.
73-242 - CACNG2
Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University.
TA309237 - CACNG2
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.
TA326519 - CACNG2
WB of rat brain lysate showing detection of ~35 kDa TARP Gamma2/Stargazin protein using Anti-TARP Gamma2/Stargazin antibody. Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2 (1:100). Lane 3: Anti-TARP Gamma2 (1:250). Lane 4: Anti-TARP Gamma2 (1:500). Lane 5: Anti-TARP Gamma2 (1:1000). Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 35 kDa. Other band(s) (unknown): ~60kDa, ~75kDa.
TA326520 - CACNG2/4/8
WB of rat brain lysate showing detection of ~35-55 kDa TARP Gamma2-4-8 (Stargazin) protein using Anti-Tarp Gamma2-4-8 antibody. Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2-4-8 (1:100). Lane 3: Anti-TARP Gamma2-4-8 (1:250). Lane 4: Anti-TARP Gamma2-4-8 (1:500). Lane 5: Anti-TARP Gamma2-4-8 (1:1000). Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2-4-8 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 55 kDa. Other band(s) (faint): ~37kDa, ~40kDa, ~75kDa.
TA328729 - CACNG2
Western blot analysis of rat brain membranes: 1. Anti-Cav?2 antibody, (1:200). 2. Anti-Cav?2 antibody, preincubated with the control peptide antigen.
CPA9256-100ul - CACNG2
Western blot analysis of CACNG2 expression in human brain (A); mouse brain (B); rat brain (C) whole cell lysates.
CPA9256-100ul - CACNG2
Immunohistochemical analysis of CACNG2 staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNG2 (C-term) antibody
  Rabbit Anti-Stargazin Antibody  
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein. Rabbit IgG Aff - Purified Ms, Rt WB
0.1 ml / €405.00
  OriGene Technologies, Inc.

CACNG2 antibody
  Rabbit Polyclonal Anti-CaVgamma2  
Western blot analysis of rat brain membranes: 1. Anti-Cav?2 antibody, (1:200). 2. Anti-Cav?2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.

CACNG2 antibody
Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Supernatant Ms, Rt ICC/IF, WB
5 ml / €490.00
  Antibodies Incorporated
 

NeuroMab

CACNG2 antibody
Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Purified Ms, Rt ICC/IF, WB
0.1 ml / €570.00
  Antibodies Incorporated
 

NeuroMab

CACNG2 antibody
Western blot analysis using gamma2 antibody on rat brain lysate. Rabbit IgG Purified Hu WB
0.1 mg / €400.00
  OriGene Technologies GmbH

CACNG2/4/8 (203-323, Cytopl. Dom.) antibody
  Mouse Monoclonal Anti-TARP Gamma2-4-8 (Stargazin) Antibody  
WB of rat brain lysate showing detection of ~35-55 kDa TARP Gamma2-4-8 (Stargazin) protein using Anti-Tarp Gamma2-4-8 antibody. Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2-4-8 (1:100). Lane 3: Anti-TARP Gamma2-4-8 (1:250). Lane 4: Anti-TARP Gamma2-4-8 (1:500). Lane 5: Anti-TARP Gamma2-4-8 (1:1000). Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2-4-8 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 55 kDa. Other band(s) (faint): ~37kDa, ~40kDa, ~75kDa. Mouse IgG2a S245-36 Purified Ms, Rt ICC/IF, WB
0.1 mg / €410.00
  OriGene Technologies, Inc.

CACNG2/4/8 antibody
Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Supernatant Ms, Rt ICC/IF, WB
5 ml / €490.00
  Antibodies Incorporated
+1 additional image

NeuroMab

CACNG2/4/8 antibody
Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Purified Ms, Rt ICC/IF, WB
0.1 ml / €570.00
  Antibodies Incorporated
+1 additional image

NeuroMab

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CACNG2 (mGFP-tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2), 200 uL, >10^7 TU/mL
Lenti ORF particles, CACNG2 (mGFP-tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2), 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.
 

9 Item(s)

per page

Available Filters

Product Type
  1. Human Lenti ORF Particle (1)
  2. Primary Antibody (8)
Clonality
  1. Monoclonal (5)
  2. Polyclonal (3)
Target
  1. CACNG2 (5)
  2. CACNG2/4/8 (3)
Property
  1. 203-323, Cytopl. Dom. (1)
  2. C-term (1)
Reactivity
  1. Mouse (Ms) (7)
  2. Rat (Rt) (7)
  3. Human (Hu) (2)
Applications
  1. Western blot / Immunoblot (WB) (8)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (5)
Presentation
  1. Purified (5)
  2. Supernatant (2)
  3. Aff - Purified (1)
Host
  1. Mouse (5)
  2. Rabbit (3)
Images
  1. 1 image (8)
Images: Applications
  1. Western blot / Immunoblot (WB) (8)
Manufacturer
  1. OriGene Technologies (5)
  2. Antibodies Incorporated (4)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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