Caspase-6 antibody
Principal name
Caspase-6 antibody
Alternative names for Caspase-6 antibody
CASP-6, CASP6, MCH2, MCH-2, Apoptotic protease Mch-2
Ncbi ID
NP_001217.2, 9606, NP_954871, NP_001217, NP_033941.3, NM_032992, NM_009811, NM_001226
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection))
Background of Caspase-6 antibody
Caspase-6 (Cysteine-Requiring Aspartate Proteases) is part of a family of intracellular cysteine proteases that cleave their substrates after aspartic acid residues. These proteases play an integral role in inducing apoptosis in cells. Procaspase-6 (Mch2), a member of the ICE/ced-3 subfamily, is an inactive proenzyme that is activated to form caspase-6 by proteolytic cleavage at certain aspartic acid residues. During cleavage, the N-terminal is removed and the proenzyme is converted into a large (p18) and small (p11) subunits. Caspase-6 has two isoforms produced by alternative splicing. Over-expression of the isoform of caspase-6 without its prodomain can induce apoptosis. The isoform does not seem to display proteolytic activity. Together with caspases-3 and -7, the isoform of caspase-6 is classified as an effector/execution caspase. Caspase-3, caspase-8 and caspase-10 can cleave procaspase-6. Active caspase-6 cleaves several other proteins such as lamins, NuMa and Keratin 18. A possible cleavage of caspases-8 and -10 in cytochrome-C dependent apoptosis was reported recently.
General readings
Nakamura,T., (2004) J. Biol. Chem. 279 (1), 626-634
















































Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306203 | Caspase-6 (Center) antibody |
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| Rabbit Polyclonal Caspase-6 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu | E, ICC/IF, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA306204 | Caspase-6 (N-term) antibody |
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| Rabbit Polyclonal Caspase-6 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu | E, ICC/IF, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA311848 | Caspase-6 antibody |
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| Rabbit polyclonal Caspase 6 (Cleaved-Asp179) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA311849 | Caspase-6 antibody |
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| Rabbit polyclonal Caspase 6 (Ser257) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA311850 | Caspase-6 antibody |
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| Rabbit polyclonal Caspase 6 (Ab-257) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA315173 | Caspase-6 antibody |
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| Rabbit polyclonal Caspase 6 (Cleaved-Asp162) antibody | |||||||
![]() |
Rabbit | IgG | Purified | Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA320213 | Caspase-6 (alpha) antibody |
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| Goat Polyclonal Caspase 6 (alpha) Antibody | |||||||
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Goat | Aff - Purified | Hu | E, WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA320214 | Caspase-6 antibody |
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| Goat Polyclonal Caspase 6 Antibody | |||||||
![]() |
Goat | Aff - Purified | Hu | E, WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA321305 | Caspase-6 antibody |
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| Anti-CASP6 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA321306 | Caspase-6 antibody |
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| Anti-CASP6 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA324510 | Caspase-6 (C-term) antibody |
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| Rabbit polyclonal CASP6 Antibody (C-term) | |||||||
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Rabbit | Ig | Aff - Purified | Hu, Ms | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA324528 | Caspase-6 antibody |
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| Rabbit polyclonal CASP6 Antibody (N-term) | |||||||
![]() |
Rabbit | IgG | Purified | Hu | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA327177 | Caspase-6 antibody |
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| Rabbit anti-CASP6 Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA336324 | Caspase-6 antibody |
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| Rabbit Polyclonal Caspase-6 Antibody | |||||||
![]() |
Rabbit | Purified | Can, Hu, Ms, Rt | IP, P, WB |
50 µl /
€335.00
|
||
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA348000 | Caspase-6 antibody |
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| Rabbit Polyclonal Anti-Caspase 6 (Cleaved-Asp179) Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AM05283PU-N | Caspase-6 antibody |
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Mouse | IgG1 | MCH2 14 1-190 | Purified | Hu | WB |
0.1 mg /
€400.00
|
| OriGene Technologies GmbH | |||||||
| AP00054PU-N | Caspase-6 (active) antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
€495.00
|
||
| OriGene Technologies GmbH | |||||||
| AP07290PU-N | Caspase-6 antibody |
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![]() |
Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
+1 additional image |
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| AP07692PU-N | Caspase-6 antibody |
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![]() |
Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
| AP08917PU-N | Caspase-6 antibody |
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![]() |
Rabbit | IgG | Purified | Hu, Ms, Rb | E, P, WB |
50 µl /
€500.00
|
|
| OriGene Technologies GmbH | |||||||



























+2 additional images











![Western Blot: Caspase 6 Antibody [TA336324] - analysis of Caspase-6 using Caspase-6 polyclonal antibody. Recombinant catalytically active caspase-6was western blotted with Active/Cleaved Caspase-6 antibody. Theantibody detected both the large and small su](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB100-56114-1-W.jpg)





