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CD11c antibody

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Principal name

CD11c antibody

Alternative names for CD11c antibody

ITGAX, Integrin alpha-X, Leu M5, CD11 antigen-like family member C, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95

SwissProt ID

E2RTG3, P20702 (Human), Q9QXH4 (Mouse)

Gene ID

3687 (ITGAX), 16411 (Itgax)

Ncbi ID

NP_000878.2, 9606, NP_067309.1, NP_000878, NM_000887, NM_021334

Available reactivities

Hu (Human), Mky (Monkey), Can (Canine), Rt (Rat), Ms (Mouse), Prim (Primate)

Available hosts

Mouse, Hamster, Rat, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), ELISA (detection) (E(detection)), Paraffin Sections (P)

Selected product citations ‐ of SM1834P

1. Pian, Y, Li, X, Zheng, Y, Wu, X, Yuan, Y, Jiang, Y. Binding of Human Fibrinogen to MRP Enhances Streptococcus suis Survival in Host Blood in a αXβ2 Integrin-dependent Manner. Sci Rep 2016, 26966, 6. PubMed PMID: 27231021.

Background of CD11c antibody

CD11c also known as Integrin alpha-X/beta-2 is a receptor for fibrinogen and recognizes the sequence G-P-R in fibrinogen. A member of the integrin alpha chain family CD11c with 1163 amino acid has seven FG-GAP repeats and a VWFA domain and is a heterodimer of an alpha and a beta subunit where alpha-X associates with beta-2. It binds with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). Recent reports suggest that CD11c helps in to capturing Ag in lymphoid tissues and acts as a DC marker, and may even act as an immunotarget for vaccine production and generation of both CD4 and CD8 T cell responses. Like CD11b, CD11c is also a cell surface adhesion receptor that is known to mediate both cell-cell and cell-matrix interactions. The functions of CD11c include phagocytosis of complement coated particles, cell migration, cytokine production by monocytes/macrophages, induction of T cell proliferation by Langerhans cells, leukocyte recruitment, capturing antigens in lymphoid tissues, and the survival of APC. It is predominantly expressed in tissue macrophages, dendritic cells, monocytes and granulocytes.

SM1834F - CD11c
Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD11c-FITC (SM1834F).
SM1834P - CD11c
Staining of human peripheral blood granulocytes with Mouse anti Human CD11c (SM1834PS).
SM1834R - CD11c
Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD11c:RPE (SM1834R).
MAB3864 - CD11c
Surface staining of human peripheral blood cells with ITGAX monoclonal antibody, clone BU15 ( Cat # MAB3864 ) conjugated with PerCP ( monocyte gate ).
MAB4353 - CD11c
Surface staining of human peripheral blood cells with ITGAX monoclonal antibody, clone BU15 (PerCP) ( Cat # MAB4353 ).
AM26635AF-N - CD11c

Flow cytometric analysis of Mouse CD11c expression on Mouse splenocytes. The staining intensity of AM26635AF-N is shown in the horizontal axis with Mouse I-Ab staining on the vertical axis.


AM26635AF-N - CD11c

Immunoprecipitation of Mouse CD11c from JAWSⅡ cells with Rat IgG2a (1) or M100-3 (2). After immunoprecipitated with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with AM26635AF-N.


AM26635FC-N - CD11c
Flow cytometric analysis of Mouse CD11c expression on Mouse splenocytes. The staining intensity of AM26635FC-N is shown in the horizontal axis with Mouse I-A b staining on the vertical axis.
AM26635BT-N - CD11c
Flow cytometric analysis of Mouse CD11c expression on JAWSII cells. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26635BT-N to the cells.
SM1834PP - CD11c
Surface staining of human peripheral blood cells with anti-CD11c (BU15) APC.

SM1834PP - CD11c
Surface staining of human peripheral blood cells with anti-CD11c (BU15) PerCP (monocyte gate).
AM50207PU-S - CD11c
FCM staining of Human PBMCs using CD11c Antibody Cat.-No AM50207PU (Clone HC1/1).
AM33408PU-N - CD11c
4% PFA Fixed and Paraffin Embedded Mouse spleen tissue section was subjected to Immunohistochemical staining of Mouse CD11c using AM33408PU-N
TA308537 - CD11c
Sample(30 ug whole cell lysate). A:H1299. B:Hep G2 . 7.5% SDS PAGE. TA308537 diluted at 1:1000
TA320390 - CD11c
Staining of normal human peripheral blood cells with Anti-Human CD11c FITC (left) and PE (right). Appropriate isotype controls were used (open histogram). Cells in the monocyte population were used for analysis.
TA320391 - CD11c
Staining of mouse splenocytes with Anti-Mouse CD11c FITC (left) and PE (right), and Anti-Human/Mouse CD45R (B220) APC. Total viable cells were used for analysis.
TA323539 - CD11c
Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ITGAX antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA323540 - CD11c
Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human liver and ovarian cancer tissue using ITGAX antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA323540 - CD11c
Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human liver and ovarian cancer tissue using ITGAX antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA324886 - CD11c
Western blot analysis of ITGAX Antibody (C-term) (Cat. #TA324886) in MDA-MB231 cell line lysates (35ug/lane). ITGAX (arrow) was detected using the purified Pab.
TA324886 - CD11c
Formalin-fixed and paraffin-embedded human hepatocarcinoma with ITGAX Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
TA324886 - CD11c
Immunofluorescence analysis of ITGAX Antibody (C-term) with paraffin-embedded human hepatocarcinoma . 0.05 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.Red counterstaining is PI.
TA324886 - CD11c
Flow cytometric analysis of SK-Br-3 cells using ITGAX Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
TA327617 - CD11c
Immunohistochemistry staining of Paraffin Hairy cell leukemia, bone marrow tissue by CD11c antibody (dilution: 1:20 - 1:80; visualization of staining: Cytoplasmic)
TA341125 - CD11c
Anti-CD11c antibody IHC of human colon, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341353 - CD11c
Anti-CD11c antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10-20 ug/ml.
TA352675 - ITGAX
Human peripheral blood granulocytes were stained with purified CD11c (clone 3.9) (filled histogram) or purified mouse IgG1, ?; isotype control (open histogram), followed by anti-mouse IgG FITC.
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD11c antibody
CD11c Hamster IgG N418 Purified Ms C, F, ICC/IF, IP
0.25 mg / €460.00
  OriGene Technologies GmbH
 

Published recently!

CD11c antibody
Flow cytometric analysis of Mouse CD11c expression on Mouse splenocytes. The staining intensity of AM26635FC-N is shown in the horizontal axis with Mouse I-A b staining on the vertical axis. Rat IgG2a 223H7 FITC Ms F
50 µg / €320.00
  OriGene Technologies GmbH
 

Published recently!

CD11c antibody
  Rabbit polyclonal antibody to CD11c (integrin, alpha X (complement component 3 receptor 4 subunit))  
Sample(30 ug whole cell lysate). A:H1299. B:Hep G2 . 7.5% SDS PAGE. TA308537 diluted at 1:1000 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €415.00
  OriGene Technologies, Inc.

CD11c antibody
  Mouse Anti-Human CD11c Purified (25 ug)  
Staining of normal human peripheral blood cells with Anti-Human CD11c FITC (left) and PE (right). Appropriate isotype controls were used (open histogram). Cells in the monocyte population were used for analysis. Mouse 3.9 Purified Hu F, P
25 µg / €155.00
  OriGene Technologies, Inc.

CD11c antibody
  Hamster Anti-Mouse CD11c Purified (100 ug)  
Staining of mouse splenocytes with Anti-Mouse CD11c FITC (left) and PE (right), and Anti-Human/Mouse CD45R (B220) APC. Total viable cells were used for analysis. Hamster N418 Purified Ms F
0.1 mg / €185.00
  OriGene Technologies, Inc.

CD11c antibody
  Anti-ITGAX Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ITGAX antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

CD11c antibody
  Anti-ITGAX Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human liver and ovarian cancer tissue using ITGAX antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

CD11c (C-term) antibody
  Rabbit polyclonal ITGAX Antibody (C-term)  
Western blot analysis of ITGAX Antibody (C-term) (Cat. #TA324886) in MDA-MB231 cell line lysates (35ug/lane). ITGAX (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+3 additional images

CD11c antibody
  Mouse Monoclonal ITGAX / CD11c Antibody  
Immunohistochemistry staining of Paraffin Hairy cell leukemia, bone marrow tissue by CD11c antibody (dilution: 1:20 - 1:80; visualization of staining: Cytoplasmic) Mouse IgG2a 5D11 Purified Hu P
1 ml / €840.00
  OriGene Technologies, Inc.

CD11c antibody
  Rabbit Polyclonal Anti-ITGAX Antibody (Internal)  
CD11c Rabbit Aff - Purified Hu P
50 µg / €425.00
  OriGene Technologies, Inc.

CD11c antibody
  Rabbit Polyclonal Anti-ITGAX Antibody (Internal)  
CD11c Rabbit Aff - Purified Hu, Mky P
50 µg / €425.00
  OriGene Technologies, Inc.

CD11c antibody
CD11c Mouse IgG1 CA11.6A1 Supernatant Can C, F, IP
2 ml / €510.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 Biotin Ms F
0.1 mg / €400.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 Biotin Ms F
25 µg / €180.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 FITC Ms F
0.1 mg / €400.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 Purified Ms C, F, ICC/IF, IP
0.1 mg / €330.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 Purified Ms C, F, IP
25 µg / €180.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Hamster IgG N418 PE Ms F
100 Tests / €480.00
  OriGene Technologies GmbH

CD11c antibody
CD11c Mouse IgG2a CBR-p150/4G1 Azide Free Hu C, F, FN
0.1 mg / €650.00
  OriGene Technologies GmbH

CD11c (alpha) antibody
Flow cytometric analysis of Mouse CD11c expression on Mouse splenocytes. The staining intensity of AM26635AF-N is shown in the horizontal axis with Mouse I-Ab staining on the vertical axis. Rat IgG2a 223H7 Azide Free Ms F, IP
0.1 mg / €320.00
  OriGene Technologies GmbH
+1 additional image

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