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CD160 antibody

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Principal name

CD160 antibody

Alternative names for CD160 antibody

BY55, Natural killer cell receptor BY55

SwissProt ID

O88875 (Mouse), O95971 (Human)

Gene ID

11126 (CD160), 54215 (Cd160)

Ncbi ID

9606, NP_008984, NP_008984.1, 10090, NM_001163496, NM_018767, NM_001163497, NM_007053

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F)

Background of CD160 antibody

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

General readings

1. Barakonyi, A., et al. J. Immunol. 173, 5349-5354
2. Bouteiller, L.P., et al. Proc. Natl. Acad. Sci. U S A. 99, 16963-16968 (2002)
3. Nikolova, M., et al. Int. Immunol., 14, 445-451 (2002)
Clone CL1-R2 is used in these references.

H00011126-B01P - CD160
CD160 MaxPab polyclonal antibody. Western Blot analysis of CD160 expression in human spleen.
H00011126-B01P - CD160
Western Blot analysis of CD160 expression in transfected 293T cell line (H00011126-T01) by CD160 MaxPab polyclonal antibody.Lane 1: CD160 transfected lysate(19.91 KDa).Lane 2: Non-transfected lysate.
H00011126-D01P - CD160
Western Blot analysis of CD160 expression in transfected 293T cell line (H00011126-T02) by CD160 MaxPab polyclonal antibody.Lane 1: CD160 transfected lysate(19.80 KDa).Lane 2: Non-transfected lysate.
H00011126-D01 - CD160
Immunoprecipitation of CD160 transfected lysate using anti-CD160 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CD160 MaxPab mouse polyclonal antibody (B01) (H00011126-B01).
ARP42342_P050 - CD160
Human THP-1; WB Suggested Anti-CD160 Antibody Titration: 0.2-1 ug/ml. Positive Control: THP-1 cell lysate; CD160 antibody - middle region (ARP42342_P050) in Human THP-1 cells using Western Blot
AM20180SU-N - CD160
Flow Cytometric analysis of CD160 expression on NK92 cells (left) and Lymphocytes (right). Open Histogram indicates the reaction of Isotypic Control to the cells. Shaded Histogram indicates the reaction of CD160 antibody AM20180SU-N to the cells.
C12076-1 - CD160
Western blot analysis of extracts from Jurkat/COLO205 cells, using CD160 Antibody. The lane on the right is treated with the synthesized peptide.
AP50839PU-N - CD160
Western blot analysis of CD160 Antibody (Center) (Cat. #AP50839PU-N) in Jurkat cell line lysates (35µg/lane). CD160 (arrow) was detected using the purified Pab.
TA320237 - CD160
C57BL/6 splenocytes were stained with 0.5 ug of Anti-Mouse CD160 Purified followed by F(ab')2 Anti-Rat IgG PE and subsequently with Anti-Mouse CD3e FITC and Anti-Mouse NK1.1 APC demonstrates staining of Anti-Mouse CD160 Purified on NK1.1+CD3- cells (red histogram and NK1.1+CD3+ cells (green histogram), as gated in the dot plot (left).
TA326654 - CD160
Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
TA326654 - CD160
Immunofluorescence of CD160 in Jurkat cells tissue with CD160 antibody at 5 ug/mL.
TA346450 - CD160
WB Suggested Anti-CD160 Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD160 antibody
  Rabbit Polyclonal CD160 Antibody  
Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+1 additional image

CD160 (Center) antibody
Western blot analysis of CD160 Antibody (Center) (Cat. #AP50839PU-N) in Jurkat cell line lysates (35µg/lane). CD160 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

2 Item(s)

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  1. Primary Antibody (2)
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  1. CD160 (2)
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  1. Human (Hu) (2)
  2. Mouse (Ms) (1)
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  1. Western blot / Immunoblot (WB) (2)
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  2. Purified (1)
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  1. Rabbit (2)
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  1. Western blot / Immunoblot (WB) (2)
  2. Immunofluorescence (IF) (1)
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