CD166 antibody

Principal name

CD166 antibody

Alternative names for CD166 antibody

ALCAM, MEMD, Activated leukocyte cell adhesion molecule

SwissProt ID

O35112 (Rat), O46634 (Canfa), O46651 (Rabit), P42292 (Chick), Q13740 (Human), Q61490 (Mouse), Q9BH13 (Bovin)

Gene ID

214 (ALCAM), 11658 (Alcam), 79559

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of CD166 antibody

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The gene was mapped to human chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166(cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD166 antibody

  Rabbit Polyclonal Anti-ALCAM Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Mouse thymus tissue, Primary antibody: (ALCAM Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

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