CD41-CD61 Complex antibody
Principal name
CD41-CD61 Complex antibody
Alternative names for CD41-CD61 Complex antibody
GPIIb-IIIa, ITGA2B, GP2B, ITGAB, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb, GP3A, CD41, CD61, Integrin alpha-IIb, Integrin beta-3, ITGB3
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Enzyme Immunoassay (E), Functional assay (FN), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of CD41-CD61 Complex antibody
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
General readings
1. III. Workshop on Ruminant Leukocyte Antigens:
Naessens J & Hopkins J: Proceedings of the 3rd workshop on ruminant leukocyte antigens. Davis, California, 16 July 1995. Vet Immunol Immunopathol 52:213-468 (1996).
2. Mateo A, Perez de la Lastra J, Moreno A, Dusinsky R, Bilka F, Simon M, Horovska L, Llanes D.: Biochemical characterization of antigens detected with anti-platelet monoclonal antibodies. Vet Immunol Immunopathol. 1996 Aug;52(4):363-70.
3. Simon M, Dusinsky R, Horovska L, Bilka F, Hluchy S.: Immunohistochemical reactivity of anti-platelet monoclonal antibodies. Vet Immunol Immunopathol. 1996 Aug;52(4):377-82.
4. Mateo A, Pintado CO, Perez de la Lastra J, Dusinsky R, Simon M, Naessens J, Llanes D.: Ruminant cluster CD41/CD61. Vet Immunol Immunopathol. 1996 Aug;52(4):251-3.
5. Naessens J, Howard CJ, Hopkins J.: Nomenclature and characterization of leukocyte differentiation antigens in ruminants. Immunol Today. 1997 Aug;18(8):365-8.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM05550FC-N | CD41-CD61 Complex antibody |
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 |
Mouse | IgG1 | 11C3 | FITC | Chk | F |
0.1 mg /
€540.00
|
| OriGene Technologies GmbH | |||||||
| AM05550PE-N | CD41-CD61 Complex antibody |
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 |
Mouse | IgG1 | 11C3 | PE | Chk | F |
100 Tests /
€610.00
|
| OriGene Technologies GmbH | |||||||
| AM09275PU-N | CD41-CD61 Complex antibody |
||||||
 |
Mouse | IgG1 | 237 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09276PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG1 | 474 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09277PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG1 | 700 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09278PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG1 | 71 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09279PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG1 | 128 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09280PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG1 | 585 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09281PU-N | CD41-CD61 Complex antibody |
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|
Mouse | IgG2a | 8 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09282PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG2b | 291 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| AM09283PU-N | CD41-CD61 Complex antibody |
||||||
|
Mouse | IgG2b | 262 | Aff - Purified | Hu | E, WB |
0.5 mg /
€470.00
|
| OriGene Technologies GmbH | |||||||
| SM3022P | CD41-CD61 Complex antibody |
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|
Mouse | IgG2 | IVA30 | Aff - Purified | Bov | C, E, F, IP |
0.1 mg /
€210.00
|
| OriGene Technologies GmbH | |||||||