CD53 antibody
Principal name
CD53 antibody
Alternative names for CD53 antibody
Cell surface glycoprotein CD53, Tetraspanin-25, MOX44, TSPAN25, Leukocyte surface antigen CD53
Ncbi ID
NP_000551.1, NP_036655.1, 9606, NM_000560, NP_000551, NP_031677.1, NM_007651, NM_001040033
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of CD53 antibody
CD53 is a member of the tetraspan family of molecules, and is expressed by all leucocytes, but is absent from red cells and platelets.
Most of the tetraspan family of molecules are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2 generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 is a glycoprotein of 32-40 kDa belonging to the tetraspans family (TM4SF). CD53 antigen is exclusivelly expressed on leucocytes (not present on platelets, red blood cells and non-hematopoietic cells). CD53 is important for signal transduction. CD53 cross-linking promotes activation of human B cells and rat macrophages.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| SM1137F | CD53 antibody |
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 |
Mouse | IgG1 | MEM-53 | FITC | Hu | F |
100 Tests /
€400.00
|
| OriGene Technologies GmbH | |||||||
| SM1137LE | CD53 antibody |
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 |
Mouse | IgG1 | MEM-53 | Low Endotoxin | Hu | C, F, FN, IP, WB |
0.1 mg /
€210.00
|
| OriGene Technologies GmbH | |||||||
| SM1137P | CD53 antibody |
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 |
Mouse | IgG1 | MEM-53 | Purified | Hu | C, F, IP, P, WB |
0.2 mg /
€460.00
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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| SM1137PS | CD53 antibody |
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|
Mouse | IgG1 | MEM-53 | Purified | Hu | C, F, FN, IP, WB |
0.1 mg /
€210.00
|
| OriGene Technologies GmbH | |||||||
| SM1137R | CD53 antibody |
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|
Mouse | IgG1 | MEM-53 | PE | Hu | F |
100 Tests /
€290.00
|
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP308095 | CD53 (transcript variant 2) |
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| Purified recombinant protein of Homo sapiens CD53 molecule (CD53), transcript variant 2 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY424639 | CD53 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR202472L2V | Lenti ORF particles, Cd53 (GFP-tagged) - Mouse CD53 antigen (Cd53), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR202472L1V | Lenti ORF particles, Cd53 (Myc-DDK-tagged) - Mouse CD53 antigen (Cd53), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
