Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Target » CDC7 antibody

CDC7 antibody

(reset)

Principal name

CDC7 antibody

Alternative names for CDC7 antibody

CDC7L1, CDC7-related kinase, HsCdc7, huCdc7, Cell division cycle 7-related protein kinase

SwissProt ID

O00311 (Human), P06243 (Yeast), Q9Z0H0 (Mouse)

Gene ID

8317 (CDC7)

Ncbi ID

9606, NP_001127891, NP_001127891.1, NP_003494.1 (Gene ID : 8317), NM_003503, NM_001134419, NM_001134420

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C)

Background of CDC7 antibody

Cell division cycle-7 (CDC7) was initially discovered as a temperature sensitive cell cycle mutant in Saccharomyces cerevisiae. CDC7 is required in the mitotic cell cycle for the initiation of DNA synthesis. CDC7 forms a complex with a Dbf4-related regulatory subunit to generate an active Ser/Thr kinase that functions in DNA replication, repair, and mitotic recombination. CDC7-Dbf4 efficiently phosphorylates several proteins that are required for the initiation of DNA replication, including five of the six minichromosome maintenance (MCM) proteins and the p180 subunit of DNA polymerase alpha-primase. CDC7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. A human homolog of the yeast CDC7 is over-expressed in some tumors and transformed cell lines.

General readings

This antibody is used in these references:
1. Kim. B. J., et al., J. Biol. Chem 281, 12041-12049 (2006)
2. Liu. P., et al., J. Biol. Chem. 281, 30631-30644 (2006)
3. Yoshizawa-Sugata, N., et al., J. Biol. Chem. 280, 13062-13070 (2005).

AM20025AF-N - CDC7
Figure 3. Immunohistochemical detection of CDC7 on Paraffin Embedded Section of Human Tonsil (germinal center) with CDC7 antibody (AM20025AF-N).
AM20025AF-N - CDC7
Figure 1. Western blot analysis of CDC7 expression in HeLa cells (Lane 1), Raji cells (Lane 2), NIH/3T3 cells (Lane 3) and Rat-1 cells (Lane 4) using CDC7 antibody (AM20025AF-N).
AM20025AF-N - CDC7
Figure 2. Immunoprecipitation of CDC7 from HeLa cells with Normal Mouse IgG (Lane 1) or AM20025AF-N (Lane 2). After immunoprecipitated with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with CDC7 antibody (AM20025AF-N).
AP20508PU-N - CDC7
Western blot (WB) analysis of Cdc7 antibody (Cat.-No.: AP20508PU-N) in extracts from Jurkat cells.
C10020-1 - CDC7
Western blot analysis of extracts from Jurkat cells, using CDC7 Antibody. The lane on the right is treated with the synthesized peptide.
TA314723 - CDC7
Western blot analysis of extracts from Jurkat cells, using CDC7 antibody.The lane on the right is treated with the synthesized peptide.
TA332874 - CDC7
Western blot analysis of extracts of various cell lines, using CDC7 antibody.
TA341015 - CDC7
Anti-CDC7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341015 - CDC7
Anti-CDC7 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341015 - CDC7
Anti-CDC7 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341016 - CDC7
Anti-CDC7 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341016 - CDC7
Anti-CDC7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341016 - CDC7
Anti-CDC7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA351065 - CDC7
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CDC7 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
TA351065 - CDC7
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using (CDC7 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDC7 antibody
  Rabbit polyclonal anti-CDC7 antibody  
Western blot analysis of extracts from Jurkat cells, using CDC7 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

CDC7 antibody
  Rabbit anti-CDC7 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using CDC7 antibody. Rabbit IgG Purified Hu
0.1 mg / €335.00
  OriGene Technologies, Inc.

CDC7 antibody
  Rabbit Polyclonal Anti-CDC7 Antibody (Kinase Domain)  
CDC7 Rabbit Aff - Purified Hu P
50 µg / €425.00
  OriGene Technologies, Inc.

CDC7 antibody
  Rabbit Polyclonal Anti-CDC7 Antibody (Kinase Domain)  
CDC7 Rabbit Aff - Purified Hu, Ms P
50 µg / €425.00
  OriGene Technologies, Inc.

CDC7 antibody
  Rabbit Polyclonal Anti-CDC7 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CDC7 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

CDC7 antibody
Figure 3. Immunohistochemical detection of CDC7 on Paraffin Embedded Section of Human Tonsil (germinal center) with CDC7 antibody (AM20025AF-N). Mouse IgG2b DCS-342 Azide Free Hu IP, P, WB
0.1 mg / €450.00
  OriGene Technologies GmbH
+2 additional images

CDC7 antibody
Western blot (WB) analysis of Cdc7 antibody (Cat.-No.: AP20508PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH

CDC7 antibody
CDC7 Rabbit Purified Hu, Ms C, E, WB
0.1 mg / €450.00
  OriGene Technologies GmbH

Lysates

Catalog No.    

CDC7 overexpression lysate
CDC7 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

CDC7 overexpression lysate
CDC7 overexpression lysate  
0.1 mg / €315.00
  OriGene Technologies, Inc.

10 Item(s)

per page

Available Filters

Product Type
  1. Lysate (2)
  2. Primary Antibody (8)
Clonality
  1. Polyclonal (7)
  2. Monoclonal (1)
Target
  1. CDC7 (8)
Reactivity
  1. Human (Hu) (8)
  2. Mouse (Ms) (3)
Applications
  1. Paraffin Sections (P) (5)
  2. Western blot / Immunoblot (WB) (4)
  3. Enzyme Immunoassay (E) (3)
  4. Frozen sections (C) (1)
  5. Immunoprecipitation (IP) (1)
Presentation
  1. Purified (4)
  2. Aff - Purified (3)
  3. Azide Free (1)
Host
  1. Rabbit (7)
  2. Mouse (1)
Images
  1. 1 image (5)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. IHC (1)
  3. Immunoprecipitation (IP) (1)
  4. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (10)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn