Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Target » CIRBP antibody

CIRBP antibody

(reset)

Principal name

CIRBP antibody

Alternative names for CIRBP antibody

A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

SwissProt ID

O93235 (Xenla), P60824 (Mouse), P60825 (Rat), P60826 (Crigr), Q14011 (Human)

Gene ID

1153 (CIRBP), 12696 (Cirbp)

Ncbi ID

9606, EAW69522, NP_001271, NP_001271.1, NM_007705

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of CIRBP antibody

CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.

General readings

1. Zeng Y, Kulkarni P, Inoue T, Getzenberg RH,
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. Journal of cellular biochemistry 2009 May 107 (1): 179-88. PMID: 19277990

H00001153-M03 - CIRBP
Detection limit for recombinant GST tagged CIRBP is approximately 0.3ng/ml as a capture antibody.
ARP40349_P050 - CIRBP
Human HepG2; WB Suggested Anti-CIRBP Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; CIRBP antibody - N-terminal region (ARP40349_P050) in Human HepG2 cells using Western Blot
H00001153-D01P - CIRBP
Western Blot analysis of CIRBP expression in transfected 293T cell line (H00001153-T02) by CIRBP MaxPab polyclonal antibody.Lane 1: CIRBP transfected lysate(18.60 KDa).Lane 2: Non-transfected lysate.
AP21511PU-N - CIRBP
AP21511PU-N CIRBP antibody staining of Mouse Testis lysate at 0.05 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
AR09973PU-L - CIRBP
Recombinant human CIRBP, 1-172 aa, His-tagged
AP50926PU-N - CIRBP
CIRBP Antibody (C-term) (Cat. #AP50926PU-N) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIRBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AP50926PU-N - CIRBP
Western blot analysis of CIRBP (arrow) using rabbit polyclonal CIRBP Antibody (C-term) (Cat. #AP50926PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CIRBP gene.
AP50926PU-N - CIRBP
Western blot analysis of CIRBP Antibody (C-term) (Cat. #AP50926PU-N) in Y79 cell line lysates (35µg/lane). CIRBP (arrow) was detected using the purified Pab.
TP301639 - CIRBP
TA311205 - CIRBP
(0.01ug/ml) staining of Mouse Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA345766 - CIRBP
WB Suggested Anti-CIRBP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1: 312500 Positive Control: A549
TA345767 - CIRBP
WB Suggested Anti-CIRBP Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate
  1. Quick-Filters:
  2. Cited (1)

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIRBP (81-91) antibody
AP21511PU-N CIRBP antibody staining of Mouse Testis lysate at 0.05 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €380.00
  OriGene Technologies GmbH
 

OriGene recommends this product for Western blotting.

CIRBP (C-term) antibody
  Goat Anti-CIRBP (aa 161-172) Antibody  
(0.01ug/ml) staining of Mouse Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

CIRBP (C-term) antibody
CIRBP Antibody (C-term) (Cat. #AP50926PU-N) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIRBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu E, P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+2 additional images

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CIRBP (transcript variant 1)
  Recombinant protein of human cold inducible RNA binding protein (CIRBP), transcript variant 1  
CIRBP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Published recently!

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cirbp (GFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cirbp (GFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

6 Item(s)

per page

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (2)
  2. Primary Antibody (3)
  3. Protein | Growth Factor (1)
Clonality
  1. Polyclonal (3)
Target
  1. CIRBP (4)
Property
  1. 81-91 (1)
  2. C-term (2)
Reactivity
  1. Human (Hu) (3)
  2. Bovine (Bov) (2)
  3. Canine (Can) (2)
  4. Mouse (Ms) (2)
  5. Rat (Rt) (2)
Applications
  1. Enzyme Immunoassay (E) (3)
  2. Western blot / Immunoblot (WB) (3)
  3. Paraffin Sections (P) (2)
Presentation
  1. Aff - Purified (3)
Host
  1. Goat (2)
  2. Rabbit (1)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn