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CUEDC2 antibody

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Principal name

CUEDC2 antibody

Alternative names for CUEDC2 antibody

C10orf66, HOYS6, CUE domain-containing protein 2

SwissProt ID

A1L131 (Rat), Q3ZBN4 (Bovin), Q9CXX9 (Mouse), Q9H467 (Human)

Gene ID

79004 (CUEDC2), 67116 (Cuedc2), 294009

Ncbi ID

9606, NP_076945, NP_076945.2, NM_024040, NP_001157762.1, NM_024192, NM_001164291, NM_001164293, NM_001164294, NM_001164295, NM_001079886

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CUEDC2 antibody

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-a and IKK-b and decrease the activation of NF-kB by decreasing the activation of IKK. CUEDC2 antibody will not cross-react with CUEDC1.

General readings

Pan X, Zhou T, et al. (2011). Nat Med. 17(6):708-14. Zhang PJ, Zhao J, et al. (2007). EMBO J. 26(7):1831-42.

AP17264PU-N - CUEDC2
Western blot analysis of CUEDC2 Antibody (C-term) (AP17264PU-N) in Y79 cell line lysates (35 µg/lane). CUEDC2 (arrow) was detected using the purified Pab.
AP22985PU-N - CUEDC2
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP22985PU-N - CUEDC2
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP22985PU-N - CUEDC2
Immunocytochemistry in HeLa cells with CUEDC2 antibody (AP22985PU-N) at 5 µg/ml.
AP22985PU-N - CUEDC2
Western blot analysis of CUEDC2 in HeLa cell lysate with CUEDC2 antibody (AP22985PU-N) at (A) 1 and (B) 2 µg/ml
AR51123PU-N - CUEDC2
TA800815 - CUEDC2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CUEDC2 (RC200790, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CUEDC2.
TA800815 - CUEDC2
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CUEDC2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
TP300790 - CUEDC2
TA306660 - CUEDC2
Western blot analysis of CUEDC2 in HeLa cell lysate with CUEDC2 antibody at (A) 1 and (B) 2 ug/mL.
TA306660 - CUEDC2
Immunocytochemistry of CUEDC2 in HeLa cells with CUEDC2 antibody at 5 ug/mL.
TA322189 - CUEDC2
Predicted band size: 32 kDa . Positive control: HepG2, Hela and 293 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3: HepG2, Hela and 293 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA337020 - CUEDC2
Western Blot: CUEDC2 Antibody [TA337020] - analysis of CUEDC2 in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide, 3) NIH 3T3 cell lysate, and 4) human spleen cell lysate using this antibody. 5 ug/ml.
TA343227 - CUEDC2
Host: Rabbit; Target Name: Cuedc2; Sample Tissue: Mouse Heart lysates; Antibody Dilution: 1.0 ug/ml
TA349838 - CUEDC2
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Human breast infiltrative duct tissue, Human fetal brain tissue, mouse brain tissue, Primary antibody: (CUEDC2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
TA349838 - CUEDC2
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (CUEDC2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
TA349838 - CUEDC2
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using (CUEDC2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CUEDC2 (C-term) antibody
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+3 additional images

Highly validated antibody!

CUEDC2 antibody
  Rabbit Polyclonal CUEDC2 Antibody  
Western blot analysis of CUEDC2 in HeLa cell lysate with CUEDC2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+1 additional image

CUEDC2 antibody
  Anti-CUEDC2 Rabbit Polyclonal Antibody  
Predicted band size: 32 kDa . Positive control: HepG2, Hela and 293 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3: HepG2, Hela and 293 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

CUEDC2 antibody
  Rabbit Polyclonal CUEDC2 Antibody  
Western Blot: CUEDC2 Antibody [TA337020] - analysis of CUEDC2 in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide, 3) NIH 3T3 cell lysate, and 4) human spleen cell lysate using this antibody. 5 ug/ml. Rabbit Purified Bov, Can, Eq, Hu, Ms, Por WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

CUEDC2 antibody
  Rabbit Polyclonal Anti-CUEDC2 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Human breast infiltrative duct tissue, Human fetal brain tissue, mouse brain tissue, Primary antibody: (CUEDC2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

CUEDC2 antibody
  CUEDC2 mouse monoclonal antibody, clone OTIH6 (formerly H6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CUEDC2 (RC200790, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CUEDC2. Mouse IgG1 OTIH6 Purified Hu WB
0.1 ml / €379.00
  OriGene Technologies, Inc.
+1 additional image

TrueMAB

CUEDC2 (C-term) antibody
Western blot analysis of CUEDC2 Antibody (C-term) (AP17264PU-N) in Y79 cell line lysates (35 µg/lane). CUEDC2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CUEDC2
  Recombinant protein of human CUE domain containing 2 (CUEDC2)  
CUEDC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

CUEDC2 overexpression lysate
CUEDC2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 5, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 6, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (GFP-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 5, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 6, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 7, 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged) - Mouse CUE domain containing 2 (Cuedc2), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cuedc2 (GFP-tagged ORF) - Rat CUE domain containing 2 (Cuedc2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (GFP-tagged ORF) - Rat CUE domain containing 2 (Cuedc2), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cuedc2 (Myc-DDK-tagged ORF) - Rat CUE domain containing 2 (Cuedc2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cuedc2 (Myc-DDK-tagged ORF) - Rat CUE domain containing 2 (Cuedc2), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

20 Item(s)

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20 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (9)
  3. Primary Antibody (7)
  4. Protein | Growth Factor (1)
  5. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (6)
  2. Monoclonal (1)
Target
  1. CUEDC2 (8)
Property
  1. C-term (2)
Reactivity
  1. Human (Hu) (7)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (2)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
  6. Equine (Eq) (1)
  7. Porcine (Por) (1)
Applications
  1. Western blot / Immunoblot (WB) (7)
  2. Enzyme Immunoassay (E) (3)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Paraffin Sections (P) (2)
Presentation
  1. Purified (5)
  2. Aff - Purified (1)
Host
  1. Rabbit (6)
  2. Mouse (1)
Images
  1. 1 image (8)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (7)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
  5. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (20)
Service
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