DDX50 antibody

Background of DDX50 antibody

DEAD box proteins, characterized byThe conserved motif Asp-Glu-Ala-Asp (DEAD), are putative R helicases.They are implicated in a number of cellular processes involving alteration of R secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based onTheir distribution patterns, some members ofThis DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.This gene encodes a DEAD box enzyme that may be involved in ribosomal R synthesis or processing.This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting thatThe two genes arose by gene duplication in evolution.This gene has pseudogenes on chromosomes 2, 3 and 4. Altertive splicing ofThis gene generates multiple transcript variants, butThe full length ture of allThe other variants but one has not been defined. [provided by RefSeq, Jul 2008].