DLGAP3 antibody
Principal name
DLGAP3 antibody
Alternative names for DLGAP3 antibody
DAP3, DAP-3, SAPAP3, Disks large-associated protein 3, SAP90/PSD-95-associated protein 3, PSD-95/SAP90-binding protein 3
Ncbi ID
Available reactivities
Available hosts
Available applications
Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)
Background of DLGAP3 antibody
SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306507 | DLGAP3 antibody |
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| Rabbit Polyclonal SAPAP3 Antibody | |||||||
 |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY421635 | DLGAP3 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC213863L2V | Lenti ORF particles, DLGAP3 (mGFP-tagged) - Human discs, large (Drosophila) homolog-associated protein 3 (DLGAP3), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,130.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR208456L2V | Lenti ORF particles, Dlgap3 (GFP-tagged ORF) - Rat discs, large (Drosophila) homolog-associated protein 3 (Dlgap3), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,860.00
|
|
| OriGene Technologies, Inc. | ||
| RR208456L1V | Lenti ORF particles, Dlgap3 (Myc-DDK-tagged ORF) - Rat discs, large (Drosophila) homolog-associated protein 3 (Dlgap3), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,670.00
|
|
| OriGene Technologies, Inc. | ||