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Ectodysplasin-A antibody

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Principal name

Ectodysplasin-A antibody

Alternative names for Ectodysplasin-A antibody

EDA, ED1, EDA2, HED, EDA1, XHED, XLHED, ED1-A1, ED1-A2, STHAGX1, Ectodermal dysplasia protein

SwissProt ID

O54693 (Mouse), Q92838 (Human), Q9BEG5 (Bovin)

Gene ID

1896 (EDA), 13607 (Eda)

Ncbi ID

9606, NP_001005609, NP_001005609.1, NP_001390.1, NM_001005610, NP_001005610, NP_001171408.1, NM_001177937, NM_001177940, NM_001177943, NM_010099, NM_001177938, NM_001177941, NM_001177939, NM_001005609, NM_001005612, NM_001399, NM_001005613

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), Por (Porcine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Ectodysplasin-A antibody

EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

General readings

Zhao,J., (2008) Br. J. Dermatol. 158 (3), 614-617

PAB4866 - Ectodysplasin-A
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EDA polyclonal antibody ( Cat # PAB4866 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
PAB4866 - Ectodysplasin-A
Western blot analysis of EDA polyclonal antibody ( Cat # PAB4866 ) in Hela cell lysate ( 35 µg/lane ) . EDA ( arrow ) was detected using the purified polyclonal antibody ( 1 : 60 dilution ) .
AP13273PU-N - Ectodysplasin-A
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EDA antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
AP13273PU-N - Ectodysplasin-A
Western blot analysis of anti-EDA Antibody (N-term) in Hela cell line lysates (35ug/lane). EDA(arrow) was detected using the purified Pab (1:60 dilution).
ARP44519_P050 - Ectodysplasin-A
Human HepG2; WB Suggested Anti-EDA Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate; EDA antibody - middle region (ARP44519_P050) in Human HepG2 cells using Western Blot
ARP44518_P050 - Ectodysplasin-A
Human 721_B; WB Suggested Anti-EDA Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:625600. Positive Control: 721_B cell lysate. EDA is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells.; EDA antibody - middle region (ARP44518_P050) in Human 721_B cells using Western Blot
TP315628 - Ectodysplasin-A
TA323177 - Ectodysplasin-A
Western blot analysis of Human lung cancer tissue using TA323177(EDA Antibody) at dilution 1/650
TA323177 - Ectodysplasin-A
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA323177(EDA Antibody)(left image) at dilution 1/40, the image on the right is treated with the synthetic peptide.(Original magnification: x200)
TA323177 - Ectodysplasin-A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ETA323177(EDA Antibody)(left image) at dilution 1/40, the image on the right is treated with the synthetic peptide.(Original magnification: x200)
TA323178 - Ectodysplasin-A
Western blot analysis of Human lung cancer tissue using TA323178(EDA Antibody) at dilution 1/130
TA327440 - Ectodysplasin-A
Western blot analysis of extracts of NCL-H460 cell line, using EDA antibody.
TA336165 - Ectodysplasin-A
WB Suggested Anti-EDA Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 625600; Positive Control: 721_B cell lysate.EDA is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
TA336166 - Ectodysplasin-A
WB Suggested Anti-EDA Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate
TA336167 - Ectodysplasin-A
Host: Rabbit; Target Name: Eda; Sample Tissue: Rat Stomach lysates; Antibody Dilution: 1.0 ug/ml
TA349124 - Ectodysplasin-A
Western blot analysis of EDA1 in mouse kidney tissue lysate with EDA1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
TA349124 - Ectodysplasin-A
Immunohistochemistry of EDA1 in mouse kidney tissue with EDA1 antibody at 5 ug/mL.
TA349124 - Ectodysplasin-A
Immunofluorescence of EDA1 in mouse kidney tissue with EDA1 antibody at 20 ug/mL.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ectodysplasin-A antibody
  Anti-EDA Rabbit Polyclonal Antibody  
Western blot analysis of Human lung cancer tissue using TA323177(EDA Antibody) at dilution 1/650 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

Ectodysplasin-A antibody
  Anti-EDA Rabbit Polyclonal Antibody  
Western blot analysis of Human lung cancer tissue using TA323178(EDA Antibody) at dilution 1/130 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Ectodysplasin-A antibody
  EDA Rabbit Polyclonal Antibody  
Western blot analysis of extracts of NCL-H460 cell line, using EDA antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Ectodysplasin-A antibody
  Rabbit Polyclonal Anti-EDA1 Antibody  
Western blot analysis of EDA1 in mouse kidney tissue lysate with EDA1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

Ectodysplasin-A antibody
  Rabbit Polyclonal Anti-EDA Antibody  
Ectodysplasin-A Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

Ectodysplasin-A (N-term) antibody
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EDA antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Ectodysplasin-A (transcript variant 3)
  Recombinant protein of human ectodysplasin A (EDA), transcript variant 3  
Ectodysplasin-A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

EDA overexpression lysate
EDA overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

8 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (6)
  3. Protein | Growth Factor (1)
Clonality
  1. Polyclonal (6)
Target
  1. Ectodysplasin-A (7)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (6)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (4)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Enzyme Immunoassay (E) (3)
  3. Paraffin Sections (P) (3)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Purified (5)
  2. Aff - Purified (1)
Host
  1. Rabbit (6)
Images
  1. 1 image (6)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (5)
  2. IHC (2)
  3. Immunofluorescence (IF) (1)
  4. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (8)
Service
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