EFHD2 antibody

Principal name

EFHD2 antibody

Alternative names for EFHD2 antibody

Swiprosin-1, SWS1, Swiprosin 1, EF-hand domain-containing protein D2

SwissProt ID

A5D7A0 (Bovin), Q4FZY0 (Rat), Q96C19 (Human), Q9D8Y0 (Mouse)

Gene ID

79180 (EFHD2), 298609 (Efhd2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Ze (Zebrafish)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of EFHD2 antibody

EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.

General readings

Olsen,J.V., (2006) Cell 127 (3), 635-648

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EFHD2 (C-term) antibody

  Goat Polyclonal Antibody against EFHD2  
TA302973 (0.1µg/ml) staining of human lymph node lysate.  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

EFHD2 antibody

  Rabbit Polyclonal EFHD2 Antibody  
Western blot analysis of EFHD2 in mouse brain tissue lysate with EFHD2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.

EFHD2 (N-term) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €425.00
  OriGene Technologies GmbH

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