Home » Target » Elastin antibody

Elastin antibody

Principal name

Elastin antibody

Alternative names for Elastin antibody

ELN, Tropoelastin

SwissProt ID

P04985 (Bovin), P07916 (Chick), P11547 (Sheep), P15502 (Human), P54320 (Mouse), Q99372 (Rat)

Gene ID

25043 (Eln), 2006 (ELN), 280781

Ncbi ID

NP_036854.1, NP_000492.2, NP_786966.1, 9606, 9913, 10116, NP_001075221, NM_012722, NM_000501, NM_001081753

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Can (Canine), Fe (Feline), GP (Guinea Pig), Gt (Goat), Por (Porcine), Sh (Sheep), Bov (Bovine)

Available hosts

Rabbit, Mouse, Guinea Pig

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Elastin antibody

Elastin is an important polymeric protein of connective tissue that imparts elasticity to vertebrate elastic tissues.
Elastin is a protein in connective tissue that is elastic and allows many tissues in the body to resume their shape after stretching or contracting. Elastin helps skin to return to its original position when it is poked or pinched. Elastin is also an important load-bearing tissue in the bodies of mammals and used in places where mechanical energy is required to be stored. Elastin is particularly abundant in large elastic blood vessels such as the aorta. It is also very important in the lungs, elastic ligaments, the skin, the bladder, and elastic cartilage.
Elastin is composed largely of glycine, proline, and other hydrophobic residues and contains multiple lysine-derived crosslinks, such as desmosines, which link the individual polypeptide chains into a rubberlike network. The hydrophobic regions of the chains, between the crosslinks, are highly mobile. The hydrophobic and crosslinking domains are coded by separate, small (27 to 114 bp) exons that are separated by large introns. The initial translation product is a 72,000-dalton polypeptide, designated tropoelastin. Elastin is made by linking many soluble tropoelastin protein molecules, in a reaction catalyzed by lysyl oxidase, to make a massive insoluble, durable cross-linked array.

General readings

1.Rosenbloom, J. : Personal Communication. Philadelphia, Pa., 4/1984
2．Urban, Z.; Riazi, S.; Seidl, T. L.; Katahira, J.; Smoot, L. B.; Chitayat, D.; Boyd, C. D.; Hinek, A.: Connection between elastin haploinsufficiency and increased cell proliferation in patients with supravalvular aortic stenosis and Williams-Beuren syndrome. Am. J. Hum. Genet. 71: 30-44, 2002.
3．Uitto, J.; Christiano, A. M.; Kahari, V.-M.; Bashir, M. M.; Rosenbloom, J. : Molecular biology and pathology of human elastin. Biochem. Soc. Trans. 19: 824-829, 1991.

Western Blot analysis of ELN expression in transfected 293T cell line (H00002006-T02) by ELN MaxPab polyclonal antibody.Lane 1: ELN transfected lysate(56.70 KDa).Lane 2: Non-transfected lysate.

H00002006-D01P

Western Blot analysis of ELN expression in transfected 293T cell line (H00002006-T01) by ELN MaxPab polyclonal antibody.Lane1:ELN transfected lysate(72.38 KDa).Lane2:Non-transfected lysate.

H00002006-B01P

Western blot analysis of Elastin expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates.

Western blot analysis of Human hepatocellular carcinoma tissue using TA323639(ELN Antibody) at dilution 1/500

TA323639

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA323639(ELN Antibody)(left image) at dilution 1/50, the image on the right is treated with the fusion protein.(Original magnification: x200)

TA323639

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA323639 (ELN Antibody)(left image) at dilution 1/50, the image on the right is treated with the fusion protein.(Original magnification: x200)

TA323639

Western blot analysis of Human hepatocellular carcinoma tissue using TA323640(ELN Antibody) at dilution 1/400

TA323640

Primary Antibodies

Catalog No.	Host	Iso.	Clone	Pres.	React.	Applications
DM230	Elastin antibody
	Mouse	IgG1	BA-4	Ascites	Can, Fe, GP, Gt, Hu, Por, Sh	C, P, WB	1 ml / €640.00
							OriGene Technologies GmbH
	Published recently!
DM230-05	Elastin antibody
	Mouse	IgG1	BA-4	Ascites	Bov, Can, Fe, GP, Gt, Hu, Por, Sh	C, P, WB	0.5 ml / €410.00
							OriGene Technologies GmbH
	Published recently!
TA323639	Elastin antibody
	Anti-ELN Rabbit Polyclonal Antibody
	Rabbit	IgG		Purified	Hu, Ms, Rt	E, WB	0.1 ml / €335.00
							OriGene Technologies, Inc.
+2 additional images
TA323640	Elastin antibody
	Anti-ELN Rabbit Polyclonal Antibody
	Rabbit	IgG		Purified	Hu, Ms, Rt	E, WB	0.1 ml / €335.00
							OriGene Technologies, Inc.
AM20634PU-N	Elastin antibody
	Mouse	IgG1	IL-4	Purified	Bov, Can, GP, Hu	IP, P	0.1 mg / €390.00
							OriGene Technologies GmbH

Rat Lenti ORF Particles

Catalog No.
RR214116L2V	Lenti ORF particles, Eln (GFP-tagged ORF) - Rat elastin (Eln), 200 uL, >10^7 TU/mL
		200 µl / €1,710.00
		OriGene Technologies, Inc.

RR214116L1V	Lenti ORF particles, Eln (Myc-DDK-tagged ORF) - Rat elastin (Eln), 200 uL, >10^7 TU/mL
		200 µl / €1,540.00
		OriGene Technologies, Inc.

Antibodies (see all»)

Kits (see all»)

Antigens

Lysates (see all»)

Tissue Slides (see all»)

Other life-science products