EXOD1 antibody

Principal name

EXOD1 antibody

Alternative names for EXOD1 antibody

Exonuclease domain-containing protein 1, KIAA1504, MGC16943

SwissProt ID

A8K979 (Human), Q5BKS4 (Mouse)

Gene ID

112479 (ERI2), 71151 (Eri2)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Gt (Goat), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of EXOD1 antibody

EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kupsco, J.M., et al. RNA 12(12):2103-2117(2006).

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EXOD1 (Center) antibody

Western blot analysis of EXOD1 Antibody Cat.-No AP51456PU-N in HL-60 cell line lysates (35ug/lane). This demonstrates the EXOD1 antibody detected the EXOD1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Lysates

Catalog No.    

ERI2 overexpression lysate

ERI2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Eri2 (GFP-tagged) - Mouse exoribonuclease 2 (Eri2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Eri2 (GFP-tagged) - Mouse exoribonuclease 2 (Eri2), 200 uL, >10^7 TU/mL  
200 µl / €1,450.00
  OriGene Technologies, Inc.

Lenti ORF particles, Eri2 (Myc-DDK-tagged) - Mouse exoribonuclease 2 (Eri2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Eri2 (Myc-DDK-tagged) - Mouse exoribonuclease 2 (Eri2), 200 uL, >10^7 TU/mL  
200 µl / €1,310.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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