FGF21 antibody
Principal name
FGF21 antibody
Alternative names for FGF21 antibody
FGF-21, Fibroblast growth factor 21
Ncbi ID
9606, NP_061986.1, NP_061986, NP_064397.1, NM_019113, NP_064397, NM_020013
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of FGF21 antibody
FGF21(Fibroblast growth factor 21) is a protein that in humans is encoded by the FGF21 gene, which is also a member of the fibroblast growth factor (FGF) family. The FGF21 gene is mapped on 19q13.33. Using RT-PCR, Fgf21 was expressed in several types of adipose tissue in mice, including subcutaneous and epididymal fat pads and brown adipose tissue. The level of Fgf21 expression in adipose tissue was comparable to that in liver. FGF21 stimulates glucose uptake in adipocytes but not in other cell types. This effect is additive to the activity of insulin. FGF21 treatment of adipocytes is associated with phosphorylation of FRS2, a protein linking FGF receptors to the Ras/MAP kinase pathway. FGF21 also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. Changes in Fgf21 expression due to suckling or nutritional manipulations were associated with changes in circulating free fatty acid and ketone body levels. In differentiated mouse brown adipocytes in culture, Fgf21 treatment increased the expression of thermogenic genes, caused higher total and uncoupled respiration, and enhanced glucose oxidation.
General readings
Inagaki T, Dutchak P, Zhao G, Ding X, Gautron L, Parameswara V, Li Y, Goetz R, Mohammadi M, Esser V, Elmquist JK, Gerard RD, Burgess SC, Hammer RE, Mangelsdorf DJ, Kliewer SA.
Endocrine Regulation of the Fasting Response by PPARalpha-Mediated Induction of Fibroblast Growth Factor 21.
Metab. 2007 Jun;5(6):415-25.
PMID: 17550777.



































































- Quick-Filters:
- Highly Validated (7)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA502953 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI1H4 (formerly 1H4) | |||||||
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Mouse | IgG1 | OTI1H4 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+7 additional images |
Top Selling product! Highly validated antibody! |
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| UM500059 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone UMAB71 | |||||||
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Mouse | IgG1 | UMAB71 | Purified | Hu | P |
0.1 ml /
€468.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
Highly validated antibody! |
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| UM570059 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone UMAB71 | |||||||
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Mouse | IgG1 | UMAB71 | Purified | Hu | P |
30 µl /
€180.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
Highly validated antibody! |
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| TA502771 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI4B2 (formerly 4B2) | |||||||
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Mouse | IgG1 | OTI4B2 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA502772 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10) | |||||||
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Mouse | IgG2a | OTI2F10 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+11 additional images |
Highly validated antibody! |
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| TA502786 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI4B4 (formerly 4B4) | |||||||
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Mouse | IgG2b | OTI4B4 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€379.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA502788 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI9E5 (formerly 9E5) | |||||||
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Mouse | IgG1 | OTI9E5 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA303289 | FGF21 antibody |
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| Goat Polyclonal Antibody against FGF21 | |||||||
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Goat | Aff - Purified | Hu | WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA349978 | FGF21 antibody |
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| Rabbit Polyclonal Anti-FGF21 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA502785 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI3G9 (formerly 3G9) | |||||||
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Mouse | IgG1 | OTI3G9 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA502787 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4) | |||||||
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Mouse | IgG2b | OTI1B4 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA502815 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI3E5 (formerly 3E5) | |||||||
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Mouse | IgG1 | OTI3E5 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA502816 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI1H5 (formerly 1H5) | |||||||
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Mouse | IgG1 | OTI1H5 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA502850 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI9A7 (formerly 9A7) | |||||||
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Mouse | IgG1 | OTI9A7 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA502868 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8) | |||||||
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Mouse | IgG1 | OTI2F8 | Purified | Hu | ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA502897 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI2B9 (formerly 2B9) | |||||||
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Mouse | IgG1 | OTI2B9 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA502954 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2) | |||||||
![]() |
Mouse | IgG1 | OTI2E2 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA502992 | FGF21 antibody |
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| FGF21 mouse monoclonal antibody, clone OTI1A9 (formerly 1A9) | |||||||
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Mouse | IgG1 | OTI1A9 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP304538 | FGF21 |
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| Recombinant protein of human fibroblast growth factor 21 (FGF21) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| TP720198 | FGF21 |
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| Recombinant protein of human fibroblast growth factor 21 (FGF21) | |||||
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Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
|
| OriGene Technologies, Inc. | |||||
















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