FGF23 antibody

Principal name

FGF23 antibody

Alternative names for FGF23 antibody

Fibroblast growth factor 23, FGF-23, Phosphatonin, HYPF, Tumor-derived hypophosphatemia-inducing factor

SwissProt ID

Q8VI82 (Rat), Q9EPC2 (Mouse), Q9GZV9 (Human)

Gene ID

8074 (FGF23), 64654 (Fgf23), 170583

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN)

Background of FGF23 antibody

Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) [MIM:193100]. ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses.
Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC) [MIM:211900]. HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues.
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FGF23 antibody

FGF23 Mouse IgG1 FGF23/638 Azide Free Hu E, FN
0.1 mg / €430.00
  OriGene Technologies GmbH

FGF23 antibody

FGF23 Mouse IgG1 FGF23/638 Purified Hu
0.1 mg / €430.00
  OriGene Technologies GmbH

FGF23 antibody

FGF23 Mouse IgG1 FGF23/638 Purified Hu
20 µg / €240.00
  OriGene Technologies GmbH

3 Item(s)

per page
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