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Fibromodulin antibody

Principal name

Fibromodulin antibody

Alternative names for Fibromodulin antibody

FMOD, FM, SLRR2E, KSPG fibromodulin, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin

SwissProt ID

O46378 (Rabit), P13605 (Bovin), P50608 (Mouse), P50609 (Rat), P51887 (Chick), Q06828 (Human)

Gene ID

2331 (FMOD), 14264 (Fmod), 64507

Ncbi ID

9606, NP_002014, NP_002014.2, NP_067330.1, NM_021355, NM_080698, NM_002023

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of Fibromodulin antibody

Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Ehret,G.B., et.al, Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)
Tillgren,V., et.al, J. Biol. Chem. 284 (42), 28543-28553 (2009).

Western Blot analysis of FMOD expression in transfected 293T cell line (H00002331-T01) by FMOD MaxPab polyclonal antibody.Lane 1: FMOD transfected lysate(41.47 KDa).Lane 2: Non-transfected lysate.

H00002331-B01P

Western Blot analysis of FMOD expression in transfected 293T cell line (H00002331-T02) by FMOD MaxPab polyclonal antibody.Lane 1: FMOD transfected lysate(41.36 KDa).Lane 2: Non-transfected lysate.

H00002331-B02

Western Blot analysis of FMOD expression in transfected 293T cell line (H00002331-T02) by FMOD MaxPab polyclonal antibody.Lane 1: FMOD transfected lysate(41.36 KDa).Lane 2: Non-transfected lysate.

H00002331-B02P

Equine; Sample Type: Equine Cartilage ExplantsPrimary Dilution: 1:500Secondary: Bio-Rad 170-5046 (Dilution: 1:100,000); FMOD antibody - N-terminal region (ARP54616_P050) in Equine cells using Western Blot

ARP54616_P050

Human 721_B; WB Suggested Anti-FMOD Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 721_B cell lysate; FMOD antibody - N-terminal region (ARP54616_P050) in Human 721_B cells using Western Blot

ARP54616_P050

Formalin-fixed and paraffin-embedded human brain tissue reacted with Fibromodulin Antibody (C-term) Cat.-No AP51689PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

AP51689PU-N

Western blot analysis of Fibromodulin Antibody (C-term) Cat.-No AP51689PU-N in mouse cerebellum tissue lysates (35ug/lane). FMOD (arrow) was detected using the purified Pab.

AP51689PU-N

Flow cytometric analysis of Hela cells using Fibromodulin Antibody (C-term) Cat.-No AP51689PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

AP51689PU-N

TP306534

WB Suggested Anti-FMOD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 721_B cell lysate

TA335029

Sample Type: Equine Cartilage ExplantsPrimary Dilution: 1: 500Secondary: Bio-Rad 170-5046 (Dilution: 1: 100, 000)

TA335029

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
AP51689PU-N	Fibromodulin (C-term) antibody
	Rabbit	Ig	Aff - Purified	Hu, Ms	F, P, WB	0.4 ml / €415.00
						OriGene Technologies GmbH
+2 additional images

Proteins & Growth Factors

Catalog No.	Species	Purity	Source
TP306534	Fibromodulin
	Recombinant protein of human fibromodulin (FMOD)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / €748.00
				OriGene Technologies, Inc.
	Published recently!

Mouse Lenti ORF Particles

Catalog No.
MR205849L1V	Lenti ORF particles, Fmod (Myc-DDK-tagged) - Mouse fibromodulin (Fmod), 200 uL, >10^7 TU/mL
		200 µl / €830.00
		OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.
RR205229L2V	Lenti ORF particles, Fmod (GFP-tagged ORF) - Rat fibromodulin (Fmod), 200 uL, >10^7 TU/mL
		200 µl / €930.00
		OriGene Technologies, Inc.

RR205229L1V	Lenti ORF particles, Fmod (Myc-DDK-tagged ORF) - Rat fibromodulin (Fmod), 200 uL, >10^7 TU/mL
		200 µl / €830.00
		OriGene Technologies, Inc.

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