FOXM1 antibody
Principal name
FOXM1 antibody
Alternative names for FOXM1 antibody
Forkhead box protein M1, FKHL16, HFH11, MPP2, WIN, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, HFH-11, HNF-3/fork-head homolog 11, Winged-helix factor from INS-1 cells, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11
Ncbi ID
9606, NP_068772, NP_068772.2, ADZ15712.1, NP_973731.1, NM_202002, NM_202003, NM_031633, NM_021953
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of FOXM1 antibody
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control D replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M. Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation. Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1. Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults. Recent studies have shown that FoxM1 expression is negatively regulated by p53. Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors. As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy.
General readings
Laoukili,J., (2008) Mol. Cell. Biol. 28 (9), 3076-3087
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA327372 | FOXM1 antibody |
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| FOXM1 Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA590329 | FOXM1 antibody |
||||||
| Rabbit Polyclonal FOXM1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu | E, ICC/IF, P |
0.1 mg /
€409.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
|||||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY404357 | FOXM1 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. | ||
| LY404358 | FOXM1 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY430897 | FOXM1 overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR203894L2V | Lenti ORF particles, Foxm1 (GFP-tagged ORF) - Rat forkhead box M1 (Foxm1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,570.00
|
|
| OriGene Technologies, Inc. | ||
| RR203894L1V | Lenti ORF particles, Foxm1 (Myc-DDK-tagged ORF) - Rat forkhead box M1 (Foxm1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,410.00
|
|
| OriGene Technologies, Inc. | ||