FPGT antibody
Principal name
FPGT antibody
Alternative names for FPGT antibody
Fucose-1-phosphate guanylyltransferase, GFPP, GDP-L-fucose pyrophosphorylase, GDP-L-fucose diphosphorylase
SwissProt ID
O14772 (Human)
Gene ID
8790 (FPGT)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)
Background of FPGT antibody
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functiol roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alterte pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alterte pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Altertive splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kise (TNNI3K) gene.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA308488 | FPGT antibody |
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| Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | P, WB |
0.1 ml /
€415.00
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| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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