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Furin antibody

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Principal name

Furin antibody

Alternative names for Furin antibody

FUR, PACE, PCSK3, Dibasic-processing enzyme, Paired basic amino acid residue cleaving enzyme

SwissProt ID

P09958 (Human), P23188 (Mouse), P23377 (Rat), Q28193 (Bovin)

Gene ID

5045 (FURIN), 18550 (Furin), 54281

Ncbi ID

9606, NP_002560, NP_002560.1, NM_001289823, NP_001074923.1, NM_019331, NM_002569

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Sh (Sheep), Can (Canine), Chimp (Chimpanzee), Eq (Equine), Mky (Monkey)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of Furin antibody

Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Furin is a calcium dependent serine endoprotease that processes numerous proproteins of different secretory pathways into their mature forms by cleaving at the carboxyl side of the recognition sequence, R-Xaa-(K/R)-R, where Xaa can be any amino acid.

General readings

Tse LV., et al. (2014) J. Virol. 88 (3), 1673-1683

PAB8731 - Furin
Western blot analysis of Furin expression in rat kidney tissue lysate.
ARP45328_P050 - Furin
Human THP-1; WB Suggested Anti-FURIN Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: THP-1 cell lysate; FURIN antibody - N-terminal region (ARP45328_P050) in Human THP-1 cells using Western Blot
AP32850PU-N - Furin
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human Furin with C-terminal MYC tag probed with AP32850PU-N (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB08896 (1ug/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
AR51848PU-N - Furin
CEK1167 - Human FURIN ELISA Kit
Representative Standard Curve
TP304279 - Furin
TA316756 - Furin
Anti-FURIN antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
TA316756 - Furin
Anti-FURIN antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
TA318986 - Furin
Western blot analysis of Furin in rat kidney tissue lysate.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Furin antibody
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human Furin with C-terminal MYC tag probed with AP32850PU-N (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB08896 (1ug/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €380.00
  OriGene Technologies GmbH
 

OriGene recommends this product for Western blotting.

Furin antibody
  FURIN Rabbit Polyclonal (aa740-790) Antibody  
Anti-FURIN antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit IgG Purified Can, Chimp, Eq, Hu, Mky, Ms, Rt
50 µg / €425.00
  OriGene Technologies, Inc.
+1 additional image

Furin antibody
  Rabbit polyclonal anti-Furin/PACE antibody  
Western blot analysis of Furin in rat kidney tissue lysate. Rabbit Purified Bov, Hu, Ms, Rt, Sh WB
0.1 mg / €355.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Furin
  Recombinant protein of human furin (paired basic amino acid cleaving enzyme) (FURIN)  
Furin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Furin
  Purified recombinant protein of Human furin (paired basic amino acid cleaving enzyme) (FURIN).  
Furin Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
10 µg / €230.00
  OriGene Technologies, Inc.
 

ELISA Kits

Catalog No.    

Human Furin ELISA Kit
Human Furin ELISA Kit  
1 kit / €500.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Furin (GFP-tagged ORF) - Rat furin (paired basic amino acid cleaving enzyme) (Furin), 200 uL, >10^7 TU/mL
Lenti ORF particles, Furin (GFP-tagged ORF) - Rat furin (paired basic amino acid cleaving enzyme) (Furin), 200 uL, >10^7 TU/mL  
200 µl / €1,600.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Furin (Myc-DDK-tagged ORF) - Rat furin (paired basic amino acid cleaving enzyme) (Furin), 200 uL, >10^7 TU/mL
Lenti ORF particles, Furin (Myc-DDK-tagged ORF) - Rat furin (paired basic amino acid cleaving enzyme) (Furin), 200 uL, >10^7 TU/mL  
200 µl / €1,440.00
  OriGene Technologies, Inc.
 

8 Item(s)

per page

Available Filters

Product Type
  1. ELISA Kit (1)
  2. Primary Antibody (3)
  3. Protein | Growth Factor (2)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (3)
Target
  1. Furin (5)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (3)
  3. Rat (Rt) (3)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
  6. Chimpanzee (Chimp) (1)
  7. Equine (Eq) (1)
  8. Monkey (Mky) (1)
  9. Sheep (Sh) (1)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (2)
  2. Aff - Purified (1)
Host
  1. Rabbit (2)
  2. Goat (1)
Images
  1. 1 image (4)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. IHC (1)
Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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