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FXR2 antibody

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Principal name

FXR2 antibody

Alternative names for FXR2 antibody

Fragile X mental retardation syndrome-related protein 2, FMR1L2

SwissProt ID

P51116 (Human), Q9WVR4 (Mouse)

Gene ID

9513 (FXR2)

Ncbi ID

NP_004851.2, 9606, NP_004851, NM_004860

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunoprecipitation (IP), Frozen Sections (C)

Background of FXR2 antibody

Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene, and in the fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 can also interact with two fragile X syndrome related factors, FXR1 and FXR2, and these proteins form heterodimers through their N-terminal coilcoiled domains. FMR1 localizes to both the nucleus and the cytoplasm, and since it contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleo-cytoplasmic transport of mRNAs.

AP06702PU-N - FXR2
Immunohistochemistry analysis of FXR2 Antibody (Cat.-No AP06702PU-N) in paraffin-embedded human muscle tissue.
AP06702PU-N - FXR2
Western blot analysis of FXR2 Antibody (Cat.-No AP06702PU-N) at 1/500 dilution in extracts from RAW264.7 cells.
AM06044SU-N - FXR2
AM06044SU-N FXR2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, cerebellum
H00009513-B01 - FXR2
Western Blot analysis of FXR2 expression in transfected 293T cell line (H00009513-T01) by FXR2 MaxPab polyclonal antibody.Lane 1: FXR2 transfected lysate(74.03 KDa).Lane 2: Non-transfected lysate.
H00009513-B01P - FXR2
Western Blot analysis of FXR2 expression in transfected 293T cell line (H00009513-T02) by FXR2 MaxPab polyclonal antibody.Lane 1: FXR2 transfected lysate(74.03 KDa).Lane 2: Non-transfected lysate.
H00009513-D01P - FXR2
FXR2 MaxPab rabbit polyclonal antibody. Western Blot analysis of FXR2 expression in mouse kidney.
H00009513-D01P - FXR2
Western Blot analysis of FXR2 expression in transfected 293T cell line (H00009513-T02) by FXR2 MaxPab polyclonal antibody.Lane 1: FXR2 transfected lysate(74.20 KDa).Lane 2: Non-transfected lysate.
ARP40557_P050 - FXR2
Human MCF-7; WB Suggested Anti-FXR2 Antibody Titration: 0.2-1 ug/ml. Positive Control: MCF7 cell lysate. FXR2 is supported by BioGPS gene expression data to be expressed in MCF7.; FXR2 antibody - middle region (ARP40557_P050) in Human MCF-7 cells using Western Blot
C10675-1 - FXR2
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using FXR2 Antibody. The picture on the right is treated with the synthesized peptide.
C10675-1 - FXR2
Immunofluorescence analysis of A549 cells, using FXR2 Antibody. The picture on the right is treated with the synthesized peptide.
C10675-1 - FXR2
Western blot analysis of extracts from COLO205 cells, using FXR2 Antibody. The lane on the right is treated with the synthesized peptide.
CPA2398-100ul - FXR2
Immunohistochemical analysis of FXR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
CPA2398-100ul - FXR2
Immunofluorescent analysis of FXR2 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
CPA2398-100ul - FXR2
Western blot analysis of FXR2 expression in Raw264.7 (A); HepG2 (B); HeLa (C) whole cell lysates.
TA309666 - FXR2
Western Blot: FXR2 Antibody - FXR2 in whole cell HeLa lysate at a concentration of 1:2500 (lane 1) and 1:500 (lane 2).
TA314923 - FXR2
Western blot analysis of extracts from COLO205 cells, using FXR2 antibody.The lane on the right is treated with the synthesized peptide.
TA314923 - FXR2
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using FXR2 antibody.The picture on the right is treated with the synthesized peptide.
TA314923 - FXR2
Immunofluorescence analysis of A549 cells, using FXR2 antibody.The picture on the right is treated with the synthesized peptide.
TA345900 - FXR2
WB Suggested Anti-FXR2 Antibody Titration: 0.2-1 ug/ml; Positive Control: MCF7 cell lysateFXR2 is supported by BioGPS gene expression data to be expressed in MCF7

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

FXR2 antibody
  Mouse Monoclonal FXR2 Antibody (1G2)  
Western Blot: FXR2 Antibody - FXR2 in whole cell HeLa lysate at a concentration of 1:2500 (lane 1) and 1:500 (lane 2). Mouse IgG1 1G2 Purified Hu, Ms C, WB
0.1 ml / €395.00
  OriGene Technologies, Inc.

FXR2 antibody
  Rabbit polyclonal anti-FXR2 antibody  
Western blot analysis of extracts from COLO205 cells, using FXR2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

FXR2 (414-658) antibody
AM06044SU-N FXR2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, cerebellum Mouse IgG1 1G2 Ascites Hu, Ms P, WB
50 µl / €425.00
  OriGene Technologies GmbH

FXR2 antibody
Immunohistochemistry analysis of FXR2 Antibody (Cat.-No AP06702PU-N) in paraffin-embedded human muscle tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

4 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (4)
Clonality
  1. Monoclonal (2)
  2. Polyclonal (2)
Target
  1. FXR2 (4)
Property
  1. 414-658 (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (4)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Paraffin Sections (P) (3)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Frozen sections (C) (1)
  5. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (2)
  2. Aff - Purified (1)
  3. Ascites (1)
Host
  1. Mouse (2)
  2. Rabbit (2)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (2)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
Manufacturer
  1. OriGene Technologies (4)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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