GABRB2 antibody
Principal name
GABRB2 antibody
Alternative names for GABRB2 antibody
GABRB-2, GABA A receptor subunit beta-2, Gamma-aminobutyric acid receptor subunit beta-2
Ncbi ID
NP_000804, 10116, NP_037089.1, NP_068711, 9606, NM_000813, NM_021911, NP_000804.1, NM_012957, NP_032096.1, NM_008070
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB)
Background of GABRB2 antibody
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990; Whiting et al., 1999; Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different Alpha-subunits of the receptor (McKernan et al., 2000; Mehta and Ticku, 1998; Ogris et al., 2004; Pöltl et al., 2003).
General readings
Rusch,D., et al., (2004) J. Biol. Chem. 279 (20), 20982-20992
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA309134 | GABRB2 antibody |
||||||
| Rabbit Anti-GABAA Receptor ß2 Antibody | |||||||
 |
Rabbit | IgG | Aff - Purified | Can, Hu, Ms, non-Human Primates, Rt | WB |
0.1 ml /
€405.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA332453 | GABRB2 antibody |
||||||
| Rabbit anti-GABRB2 Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
| OriGene Technologies, Inc. | |||||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY400287 | GABRB2 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. | ||
| LY411881 | GABRB2 overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. | ||
| LY429661 | GABRB2 overexpression lysate |
|
|
0.1 mg /
€315.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC217467L2V | Lenti ORF particles, GABRB2 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, beta 2 (GABRB2), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,210.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR211875L2V | Lenti ORF particles, Gabrb2 (GFP-tagged ORF) - Rat gamma-aminobutyric acid (GABA) A receptor, beta 2 (Gabrb2), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,150.00
|
|
| OriGene Technologies, Inc. | ||
| RR211875L1V | Lenti ORF particles, Gabrb2 (Myc-DDK-tagged ORF) - Rat gamma-aminobutyric acid (GABA) A receptor, beta 2 (Gabrb2), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,030.00
|
|
| OriGene Technologies, Inc. | ||