Grancalcin antibody
Principal name
Grancalcin antibody
Alternative names for Grancalcin antibody
GCA, GCL
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)
Background of Grancalcin antibody
GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion.
Immunofluorescence of monoclonal antibody to GCA on MCF-7 cell . [antibody concentration 10 ug/ml]
GCA monoclonal antibody (M01), clone 2F5 Western Blot analysis of GCA expression in MCF-7 ( Cat # L046V1 ).
GCA monoclonal antibody (M04), clone 2F11. Western Blot analysis of GCA expression in IMR-32(Cat # L008V1 ).
Recombinant human GCA, 1-217aa, His-tagged
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP302677 | Grancalcin |
||||
| Recombinant protein of human grancalcin, EF-hand calcium binding protein (GCA) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| TP720123 | Grancalcin |
||||
| Recombinant protein of human grancalcin, EF-hand calcium binding protein (GCA) | |||||
 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY415909 | GCA overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR202518L2V | Lenti ORF particles, Gca (GFP-tagged) - Mouse grancalcin (Gca), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR202518L1V | Lenti ORF particles, Gca (Myc-DDK-tagged) - Mouse grancalcin (Gca), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||