GSK3 beta antibody
Principal name
GSK3 beta antibody
Alternative names for GSK3 beta antibody
GSK-3 beta, Glycogen synthase kinase-3 beta, GSK3B
Ncbi ID
NP_001139628.1, 9606, 10116, NP_114469.1, NP_001139628, NP_002084, NM_002093, NP_062801.1, NM_019827, NM_032080
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F)
Background of GSK3 beta antibody
Glycogen synthase kise 3 (GSK3) is a proline-directed serine/threonine protein kise that was origilly identified for its role in glycogen metabolism; however, subsequently it was shown to serve pleiotropic functions, including embryonic development, gene transcription, and neurol cell function. Mammalian GSK has two isoforms encoded by distinct genes: GSK3A produces a 51-kD GSK3-alpha protein and GSK3B a 47-kD GSK3-beta protein. Phosphorylation of Tyr279/Tyr216 on GSK3alpha/beta is important for enzymatic activity, whereas ictivation of GSK3 can be achieved through phosphorylation of Ser21/Ser9 residues within the N-termil domain on GSK3-alpha/beta, respectively. Upstream kises PKA, AKT/PKB, PKC, p90RSK/MAPKAP and p70S6K are known to phosphorylate Ser9 of GSK3-beta. Furthermore, GSK3 is also regulated via interactions with WNT ligand and its receptor Frizzled/co-receptor LRP5/6, and this interaction releases GSK3 from a multi-protein complex formed by beta-catenin, axin, and adenomatous polyposis coli (APC), which prevents GSK3-mediated beta-catenin degradation and induces beta-catenin-dependent gene transcription. GSK3 is one of the few sigling mediators that play central roles in a diverse range of sigling pathways, including those activated by WNT, hedgehog, growth factors, cytokines, and G protein-coupled ligands. GSK3 dysregulation, particularly hyperactivation, with various pathological conditions, including diabetes mellitus, obesity, inflammation, neurological disorders, and tumorigenesis.
General readings
Castaño Z. et al.The neuron-specific isoform of glycogen synthase kinase-3β is required for axon growth. Journal of Neurochemistry, April 2010, Volume 113, Issue 1, pages 117–130.


















































































- Quick-Filters:
- Highly Validated (3)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP02546PU-N | GSK3 beta antibody |
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Rabbit | Aff - Purified | Hu, Ms | ICC/IF, P, WB |
0.1 mg /
€300.00
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| AP02546PU-S | GSK3 beta antibody |
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Rabbit | Aff - Purified | Hu, Ms | ICC/IF, P, WB |
50 µg /
€230.00
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| AP22887PU-N | GSK3 beta antibody |
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Rabbit | Purified | Bov, Hu, Ms, Rt | ICC/IF, P, WB |
50 µg /
€425.00
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| TA309159 | GSK3 beta antibody |
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| Rabbit Anti-Glycogen synthase kinase 3 B (GSK3B) (Ser9) Antibody (Phospho-Specific) | |||||||
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Rabbit | IgG | Purified | Rt | WB |
0.1 ml /
€405.00
|
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| OriGene Technologies, Inc. | |||||||
| TA313125 | GSK3 beta antibody |
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| Rabbit polyclonal GSK3beta (Ab-9) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA313126 | GSK3 beta antibody |
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| Rabbit polyclonal GSK3beta (Ser9) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
| TA317698 | GSK3 beta (4-12) pSer9 antibody |
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| GSK3B / GSK3 Beta Rabbit Polyclonal (pSer9) Antibody | |||||||
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Rabbit | Aff - Purified | Hu | E, ICC/IF, IP, P, WB |
50 µg /
€425.00
|
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| OriGene Technologies, Inc. | |||||||
| TA319263 | GSK3 beta pSer9 antibody |
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| Rabbit polyclonal GSK3 Beta phospho S9 antibody | |||||||
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Rabbit | Aff - Purified | Hu | E, IP, P, WB |
0.1 mg /
€515.00
|
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| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA323060 | GSK3 beta antibody |
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| Anti-GSK3B Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA323991 | GSK3 beta antibody |
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| Anti-GSK3B (Phospho-Tyr216) Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA324570 | GSK3 beta antibody |
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| Rabbit polyclonal Mouse Gsk3b Antibody (N-term) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA324769 | GSK3 beta antibody |
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| Rabbit polyclonal Bi-Phospho-GSK3B(S21/29) Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA326007 | GSK3 beta antibody |
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| Rabbit Polyclonal GSK3 beta Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA326008 | GSK3 beta antibody |
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| Rabbit Polyclonal GSK3 beta (Ser9) Antibody (Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA326426 | GSK3 beta antibody |
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| Rabbit polyclonal GSK-3Beta Antibody | |||||||
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Rabbit | Purified | Bov, Hu, Ms, Rt | WB |
0.1 mg /
€355.00
|
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| OriGene Technologies, Inc. | |||||||
| TA327940 | GSK3 beta antibody |
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| Rabbit Polyclonal anti-GSK-3ß Antibody | |||||||
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Rabbit | IgG | Poly6042 | Purified | Hu, Ms | WB |
0.2 ml /
€255.00
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA333208 | GSK3 beta antibody |
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| Phospho-GSK3B-S9 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
| TA336772 | GSK3 beta antibody |
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| Mouse Monoclonal GSK-3 beta Antibody (3D10) | |||||||
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Mouse | IgG2a | 3D10 | Purified | Hu, Ms, Prim, Rt | C, E, F, ICC/IF, P, WB |
0.1 ml /
€415.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
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| AM08186PU-N | GSK3 beta antibody |
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Mouse | IgG2a | SBGSK3a4 | Purified | Hu, Ms, Rt | E, IP, WB |
0.1 mg /
€460.00
|
| OriGene Technologies GmbH | |||||||
| AM08186SE-N | GSK3 beta antibody |
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Mouse | IgG2a | SBGSK3a4 | Sepharose | Hu, Ms, Rt | E, IP, WB |
50 Tests /
€600.00
|
| OriGene Technologies GmbH | |||||||

















+3 additional images













![Western Blot: GSK3 beta Antibody (3D10) [TA336772] - Western blot analysis using GSK3 beta mouse mAb against A549 (1), K562 (2), PC-12 (3), NIH/3T3 (4), and HEK293 (5) cell lysates.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP1-47470-1-W.jpg)