GSTA1 antibody

Principal name

GSTA1 antibody

Alternative names for GSTA1 antibody

Glutathione S-transferase A1, GSTA1-1, GTH1, GST-epsilon, HA subunit 1, GST class-alpha member 1

SwissProt ID

P00502 (Rat), P08263 (Human), P13745 (Mouse), P51781 (Pig), P81706 (Cavpo), Q08392 (Chick), Q08863 (Rabit), Q28035 (Bovin)

Gene ID

2938 (GSTA1), 14857 (Gsta1), 24422 (Gsta2)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of GSTA1 antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]

General readings

Rossi D., et al. (2009) Leukemia. 23(6):1118-26.
Hou L., et al. (2007) J Biol Chem. 282(32):23264-74.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GSTA1 antibody

  Rabbit polyclonal antibody to GSTA1 (glutathione S-transferase A1)  
GSTA1 antibody detects GSTA1 protein by Western blot analysis. A. 50 ug mouse liver lysate/extract. 12 % SDS-PAGE. GSTA1 antibody (TA308419) dilution: 1:5000 Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €415.00
  OriGene Technologies, Inc.

GSTA1 antibody

  GSTA1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of mouse liver cell lines, using GSTA1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

GSTA1 antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 2F7 Purified Hu E, P, WB
50 µg / €475.00
  OriGene Technologies GmbH

GSTA1 antibody

(LEFT) Western blot analysis of GSTA1 Antibody (AP18041PU-N) in HepG2 cell line lysates (35ug/lane). GSTA1 (arrow) was detected using the purified Pab. (Middle) Western blot analysis of GSTA1 Antibody (AP18041PU-N) in mouse stomach tissue lysates (35ug/lane). GSTA1 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of GSTA1 (arrow) using rabbit polyclonal GSTA1 Antibody (AP18041PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GSTA1 gene (Lane 2) . Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

GSTA1

  Recombinant protein of human glutathione S-transferase alpha 1 (GSTA1)  
GSTA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

GSTA1 overexpression lysate

GSTA1 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gsta1 (GFP-tagged) - Mouse glutathione S-transferase, alpha 1 (Ya) (Gsta1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gsta1 (GFP-tagged) - Mouse glutathione S-transferase, alpha 1 (Ya) (Gsta1), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gsta1 (Myc-DDK-tagged) - Mouse glutathione S-transferase, alpha 1 (Ya) (Gsta1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gsta1 (Myc-DDK-tagged) - Mouse glutathione S-transferase, alpha 1 (Ya) (Gsta1), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Gsta2 (GFP-tagged ORF) - Rat glutathione S-transferase A2 (Gsta2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gsta2 (GFP-tagged ORF) - Rat glutathione S-transferase A2 (Gsta2), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, Gsta2 (Myc-DDK-tagged ORF) - Rat glutathione S-transferase A2 (Gsta2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Gsta2 (Myc-DDK-tagged ORF) - Rat glutathione S-transferase A2 (Gsta2), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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