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GTF3C3 antibody

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Principal name

GTF3C3 antibody

Alternative names for GTF3C3 antibody

Transcription factor IIIC subunit gamma, TFIIIC 102 kDa subunit, TFIIIC102, TFIIIC gamma, General transcription factor 3C polypeptide 3

SwissProt ID

Q9Y5Q9 (Human)

Gene ID

9330 (GTF3C3)

Ncbi ID

9606, NP_036218, NP_001193703.1, NM_012086

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Paraffin Sections (P)

Background of GTF3C3 antibody

RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division. Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes. The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas. TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells. The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells. In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

General readings

Zhan,Y., et al., (2002) Cell Death Differ. 9 (4), 439-447

H00009330-M01 - GTF3C3
GTF3C3 monoclonal antibody (M01), clone 2D8. Western Blot analysis of GTF3C3 expression in NIH/3T3 ( Cat # L018V1 ).
H00009330-M01 - GTF3C3
GTF3C3 monoclonal antibody (M01), clone 2D8. Western Blot analysis of GTF3C3 expression in Raw 264.7 ( Cat # L024V1 ).
H00009330-M01 - GTF3C3
GTF3C3 monoclonal antibody (M01), clone 2D8 Western Blot analysis of GTF3C3 expression in Hela NE ( Cat # L013V3 ).
H00009330-M02 - GTF3C3
Western blot analysis of GTF3C3 over-expressed 293 cell line, cotransfected with GTF3C3 Validated Chimera RNAi ( Cat # H00009330-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with GTF3C3 monoclonal antibody (M02), clone 3D9 (Cat # H00009330-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
H00009330-M02 - GTF3C3
Western Blot analysis of GTF3C3 expression in transfected 293T cell line by GTF3C3 monoclonal antibody (M02), clone 3D9.Lane 1: GTF3C3 transfected lysate(101.3 KDa).Lane 2: Non-transfected lysate.
H00009330-M02 - GTF3C3
GTF3C3 monoclonal antibody (M02), clone 3D9 Western Blot analysis of GTF3C3 expression in Hela NE ( Cat # L013V3 ).
ARP35841_T100 - GTF3C3
Human HepG2; WB Suggested Anti-GTF3C3 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in HepG2.; GTF3C3 antibody - N-terminal region (ARP35841_T100) in Human HepG2 cells using Western Blot
H00009330-B01 - GTF3C3
Immunofluorescence of purified MaxPab antibody to GTF3C3 on HeLa cell. [antibody concentration 10 ug/ml]
H00009330-B01 - GTF3C3
Western Blot analysis of GTF3C3 expression in transfected 293T cell line (H00009330-T01) by GTF3C3 MaxPab polyclonal antibody.Lane 1: GTF3C3 transfected lysate(97.46 KDa).Lane 2: Non-transfected lysate.
H00009330-B01 - GTF3C3
GTF3C3 MaxPab polyclonal antibody. Western Blot analysis of GTF3C3 expression in Hela NE.
H00009330-D01P - GTF3C3
GTF3C3 MaxPab rabbit polyclonal antibody. Western Blot analysis of GTF3C3 expression in human kidney.
H00009330-D01P - GTF3C3
Western Blot analysis of GTF3C3 expression in transfected 293T cell line (H00009330-T01) by GTF3C3 MaxPab polyclonal antibody.Lane 1: GTF3C3 transfected lysate(101.30 KDa).Lane 2: Non-transfected lysate.
ARP38949_P050 - GTF3C3
Human 721_B; WB Suggested Anti-GTF3C3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in 721_B.; GTF3C3 antibody - N-terminal region (ARP38949_P050) in Human 721_B cells using Western Blot
AP20464PU-N - GTF3C3
Immunohistochemistry (IHC) analyzes of TFIIIC102 antibody (Cat.-No.: AP20464PU-N) in paraffin-embedded human brain tissue.
AP20464PU-N - GTF3C3
Western blot (WB) analysis of TFIIIC102 antibody (Cat.-No.: AP20464PU-N) in extracts from 293 cell.
C11971-1 - GTF3C3
Western blot analysis of extracts from 293 cells, using TF3C3 Antibody. The lane on the right is treated with the synthesized peptide.
CPA2381-100ul - GTF3C3
Immunohistochemical analysis of GTF3C3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
CPA2381-100ul - GTF3C3
Western blot analysis of GTF3C3 expression in HeLa (A) whole cell lysates.
TA314896 - GTF3C3
Western blot analysis of extracts from 293 cells, using TF3C3 antibody.The lane on the right is treated with the synthesized peptide.
TA339449 - GTF3C3
WB Suggested Anti-GTF3C3 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysateGTF3C3 is supported by BioGPS gene expression data to be expressed in HepG2
TA343677 - GTF3C3
WB Suggested Anti-GTF3C3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate. GTF3C3 is supported by BioGPS gene expression data to be expressed in 721_B

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

GTF3C3 antibody
  Rabbit polyclonal anti-TF3C3 antibody  
Western blot analysis of extracts from 293 cells, using TF3C3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

GTF3C3 antibody
Immunohistochemistry (IHC) analyzes of TFIIIC102 antibody (Cat.-No.: AP20464PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

GTF3C3 overexpression lysate
GTF3C3 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

3 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. GTF3C3 (2)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (2)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (3)
Service
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