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HAT1 antibody

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Principal name

HAT1 antibody

Alternative names for HAT1 antibody

Histone acetyltransferase type B catalytic subunit

SwissProt ID

O14929 (Human), Q12341 (Yeast), Q5M939 (Rat), Q8BY71 (Mouse)

Gene ID

8520 (HAT1), 107435 (Hat1), 296501

Ncbi ID

9606, NP_003633, NP_003633.1, NP_080391.2, NM_001009657, NM_001033085, NP_001009657.1

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Por (Porcine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of HAT1 antibody

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.

General readings

Marmorstein R., et al. (2001) J Mol Biol. 311(3):433-44.

AP11103PU-N - HAT1
Western blot analysis of KAT1 (HAT1) Antibody (N-term) Cat.-No AP11103PU-N in HL60 cell line lysates (35ug/lane). HAT1 (arrow) was detected using the purified Pab.
AP11104PU-N - HAT1
Western blot analysis of HAT1 Antibody (C-term) Cat.-No AP11104PU-N in 293, HepG2, Jurkat cell line lysates (35ug/lane). HAT1 (arrow) was detected using the purified Pab.
PAB8744 - HAT1
Western blot analysis of HAT1 expression in Jurkat cell lysate. The antibody recognizes 50 kDa HAT-1 from samples of human, mouse and rat origins.
AR09406PU-L - HAT1
AR09406PU-L - HAT1
Recombinant human HAT1, 20-341 aa, His-tagged: 15% SDS-PAGE (3 µg)
AP20234PU-N - HAT1
Western blot analysis of HAT1 antibody (AP20234PU-N) in extracts from LOVO cells.
C0356-1 - HAT1
Western blot analysis of extracts from K562 cells, using HAT Antibody. The lane on the right is treated with the synthesized peptide.
CPA2292-100ul - HAT1
Western blot analysis of HAT1 expression in HeLa (A); BT20 (B); A431 (C); HEK293T (D) whole cell lysates.
TA311666 - HAT1
Western blot analysis of extracts from LOVO cells, using HAT antibody.The lane on the right is treated with the synthesized peptide.
TA332983 - HAT1
Western blot analysis of extracts of various cell lines, using HAT1 antibody.
TA332983 - HAT1
Immunofluorescence analysis of U2OS cell using HAT1 antibody.
TA347486 - HAT1
Western blot analysis on LOVO cell lysate using HAT Antibody
TA346716 - Hat1
WB Suggested Anti-Hat1 Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Pancreas
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8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HAT1 antibody
  Rabbit polyclonal anti-HAT1 (HAT) antibody  
Western blot analysis of extracts from LOVO cells, using HAT antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

HAT1 antibody
  Rabbit anti-HAT1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using HAT1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.
+1 additional image

HAT1 antibody
  Rabbit Polyclonal Anti-HAT Antibody  
Western blot analysis on LOVO cell lysate using HAT Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

HAT1 (N-term) antibody
Western blot analysis of KAT1 (HAT1) Antibody (N-term) Cat.-No AP11103PU-N in HL60 cell line lysates (35ug/lane). HAT1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

HAT1 (C-term) antibody
Western blot analysis of HAT1 Antibody (C-term) Cat.-No AP11104PU-N in 293, HepG2, Jurkat cell line lysates (35ug/lane). HAT1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

HAT1 antibody
Western blot analysis of HAT1 antibody (AP20234PU-N) in extracts from LOVO cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €370.00
  OriGene Technologies GmbH

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hat1 (GFP-tagged ORF) - Rat histone acetyltransferase 1 (Hat1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Hat1 (GFP-tagged ORF) - Rat histone acetyltransferase 1 (Hat1), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Hat1 (Myc-DDK-tagged ORF) - Rat histone acetyltransferase 1 (Hat1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Hat1 (Myc-DDK-tagged ORF) - Rat histone acetyltransferase 1 (Hat1), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

8 Item(s)

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Available Filters

Product Type
  1. Primary Antibody (6)
  2. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (6)
Target
  1. HAT1 (6)
Property
  1. C-term (1)
  2. N-term (1)
Reactivity
  1. Human (Hu) (6)
  2. Mouse (Ms) (4)
  3. Rat (Rt) (4)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (5)
  2. Aff - Purified (1)
Host
  1. Rabbit (6)
Images
  1. 1 image (6)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Immunofluorescence (IF) (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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