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HBP1 antibody

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Principal name

HBP1 antibody

Alternative names for HBP1 antibody

HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1

SwissProt ID

O60381 (Human), Q2KJ34 (Bovin), Q62661 (Rat), Q8R316 (Mouse)

Gene ID

26959 (HBP1), 73389 (Hbp1)

Ncbi ID

NP_036389, NP_036389.2, 9606, AAH22329.1, NP_694878.2, NM_153198, NM_177993, NM_012257

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of HBP1 antibody

The HMG-box protein-1 (HBP1) is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest. Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

General readings

Paulson,K.E., (2007) Cancer Res. 67 (13), 6136-6145

ARP38976_P050 - HBP1
Human Jurkat; WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; HBP1 antibody - N-terminal region (ARP38976_P050) in Human Jurkat cells using Western Blot
AP06640PU-N - HBP1
Immunohistochemistry (IHC) analyzes of HBP1 antibody (Cat.-No.: AP06640PU-N) in paraffin-embedded human brain tissue.
AP06640PU-N - HBP1
Western blot (WB) analysis of HBP1 antibody (Cat.-No.: AP06640PU-N) in extracts from hela cells.
ARP38977_P050 - HBP1
Human HeLa; WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate. HBP1 is supported by BioGPS gene expression data to be expressed in HeLa.; HBP1 antibody - middle region (ARP38977_P050) in Human HeLa cells using Western Blot
ARP32559_P050 - HBP1
Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; HBP1 antibody - middle region (ARP32559_P050) in Hum. Adult Placenta cells using Western Blot
ARP32559_P050 - HBP1
Hum. Fetal Lung; Host:Rabbit. Target Name:HBP1. Sample Tissue:Human Fetal Lung. Antibody Dilution: 1.0ug/ml.; HBP1 antibody - middle region (ARP32559_P050) in Hum. Fetal Lung cells using Western Blot
ARP32559_P050 - HBP1
Hum. Fetal Muscle; Host:Rabbit. Target Name:HBP1. Sample Tissue:Human Fetal Muscle. Antibody Dilution: 1.0ug/ml.; HBP1 antibody - middle region (ARP32559_P050) in Hum. Fetal Muscle cells using Western Blot
ARP32559_P050 - HBP1
Human Jurkat; WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; HBP1 antibody - middle region (ARP32559_P050) in Human Jurkat cells using Western Blot
A1035-1 - HBP1
Western blot analysis of extracts from A549 cells treated with PMA 125ng/ml 30', using HBP1 (Phospho-Ser402) Antibody. The lane on the right is treated with the synthesized peptide.
C10135-1 - HBP1
Western blot analysis of extracts from COS7 cells, using HBP1 Antibody. The lane on the right is treated with the synthesized peptide.
CPA2619-100ul - HBP1
Western blot analysis of HBP1 (pS402) expression in HEK293T PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates.
CPA3403-100ul - HBP1
Immunohistochemical analysis of HBP1 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
CPA3403-100ul - HBP1
Western blot analysis of HBP1 expression in SKBR3 (A); U937 (B) whole cell lysates.
TA315351 - HBP1
Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.The lane on the right is treated with the synthesized peptide.
TA330605 - HBP1
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate
TA330605 - HBP1
2Hum. Adult Placenta; Host: Rabbit; Target Name: CHAD; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0ug/ml
TA330605 - HBP1
Host:Rabbit; Target Name:HBP1; Sample Tissue:Human Fetal Muscle; Antibody Dilution: 1.0ug/ml
TA330605 - HBP1
Host:Rabbit; Target Name:HBP1; Sample Tissue:Human Fetal Lung; Antibody Dilution: 1.0ug/ml
TA343692 - HBP1
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate
TA343693 - HBP1
WB Suggested Anti-HBP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate. HBP1 is supported by BioGPS gene expression data to be expressed in HeLa
TA347543 - HBP1
Western blot analysis on A549 cell lysate using HBP1 Antibody

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HBP1 antibody
  Rabbit polyclonal anti-HBP1 antibody  
Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

HBP1 antibody
  Rabbit Polyclonal Anti-HBP1 Antibody  
Western blot analysis on A549 cell lysate using HBP1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

HBP1 antibody
Immunohistochemistry (IHC) analyzes of HBP1 antibody (Cat.-No.: AP06640PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hbp1 (GFP-tagged) - Mouse high mobility group box transcription factor 1 (Hbp1), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Hbp1 (GFP-tagged) - Mouse high mobility group box transcription factor 1 (Hbp1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,220.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Hbp1 (Myc-DDK-tagged) - Mouse high mobility group box transcription factor 1 (Hbp1), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Hbp1 (Myc-DDK-tagged) - Mouse high mobility group box transcription factor 1 (Hbp1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,090.00
  OriGene Technologies, Inc.
 

5 Item(s)

per page

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (2)
  2. Primary Antibody (3)
Clonality
  1. Polyclonal (3)
Target
  1. HBP1 (3)
Reactivity
  1. Human (Hu) (3)
  2. Mouse (Ms) (3)
  3. Rat (Rt) (3)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Enzyme Immunoassay (E) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Purified (2)
  2. Aff - Purified (1)
Host
  1. Rabbit (3)
Images
  1. 1 image (3)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (5)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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  • orders: ordering-de@origene.com
 
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