HDAC2 antibody
Principal name
HDAC2 antibody
Alternative names for HDAC2 antibody
Histone deacetylase 2, HD2
Ncbi ID
NP_001518.3, 9606, NP_001518, NM_001527, NP_032255.2, NM_008229
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), ChIP assay (ChIP)
Background of HDAC2 antibody
Acetylation of the histone tail causes chromatin to adopt an "open" conformation, allowing increased accessibility of transcription factors to D. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate transcription. HAT complexes interact with sequence-specific activator proteins to target specific genes. In addition to histones, HATs can acetylate nonhistone proteins, suggesting multiple roles for these enzymes. In contrast, histone deacetylation promotes a "closed" chromatin conformation and typically leads to repression of gene activity. Mammalian histone deacetylases can be divided into three classes on the basis of their similarity to various yeast deacetylases. Class I proteins (HDACs 1, 2, 3, and 8) are related to the yeast Rpd3-like proteins, those in class II (HDACs 4, 5, 6, 7, 9, and 10) are related to yeast Hda1-like proteins, and class III proteins are related to the yeast protein Sir2. Inhibitors of HDAC activity are now being explored as potential therapeutic cancer agents.HDAC1 and HDAC2 are highly homologous and are involved in histone deacetylation, chromatin remodeling and transcriptiol repression. Both proteins are found together in numerous complexes including the nucleosome remodeling and deacetylation complex (NuRD), MeCP1, and the mSin3A corepressor complex.
General readings
Ishikawa, F., et al. Oncogene 29(6):909-919(2010)
Bush, E.W., et al. Circ. Res. 106(2):272-284(2010)
Krishnan, M., et al. Oncogene 29(2):305-312(2010)
Lehmann, A., et al. BMC Cancer 9, 395 (2009)
Hassig, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 95(7):3519-3524(1998)





































































- Quick-Filters:
- Highly Validated (4)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA590734 | HDAC2 antibody |
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| Rabbit Polyclonal HDAC2 Antibody | |||||||
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Rabbit | IgG | Purified | Can, Hu, Mky, Ms, Rt | E, P, WB |
0.1 mg /
€409.00
|
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| OriGene Technologies, Inc. | |||||||
+8 additional images |
Highly validated antibody! |
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| TA808327 | HDAC2 antibody |
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| HDAC2 mouse monoclonal antibody, clone OTI7E10 (formerly 7E10) | |||||||
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Mouse | IgG1 | OTI7E10 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+17 additional images |
Highly validated antibody! |
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| AP08014PU-N | HDAC2 pSer394 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€300.00
|
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| AP08014PU-S | HDAC2 pSer394 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
50 µg /
€230.00
|
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| TA310002 | HDAC2 antibody |
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| Rabbit anti-HDAC2 (Phospho-Ser394) polyclonal antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€355.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA313168 | HDAC2 antibody |
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| Rabbit polyclonal HDAC2 (Ab-394) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA313169 | HDAC2 antibody |
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| Rabbit polyclonal HDAC2 (Ser394) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA323156 | HDAC2 antibody |
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| Anti-HDAC2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA323157 | HDAC2 antibody |
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| Anti-HDAC2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA323158 | HDAC2 antibody |
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| Anti-HDAC2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA325112 | HDAC2 (Center) antibody |
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| Rabbit polyclonal HDAC2 Antibody (Center) | |||||||
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Rabbit | Ig | Aff - Purified | Hu | F, ICC/IF, P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
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| TA325510 | HDAC2 antibody |
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| Rabbit Polyclonal HDAC2 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA325512 | HDAC2 antibody |
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| Rabbit Polyclonal HDAC2 (Ser394) Antibody (Phospho-specific) | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA327261 | HDAC2 antibody |
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| HDAC2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA328156 | HDAC2 antibody |
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| Mouse monoclonal anti-HDAC2 antibody (Center) | |||||||
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Mouse | IgG1 | 1194CT18.5.1 | Purified | Hu | WB |
0.4 ml /
€415.00
|
| OriGene Technologies, Inc. | |||||||
| TA347136 | HDAC2 antibody |
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| Mouse Monoclonal HDAC2 Antibody | |||||||
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Mouse | IgG1 | Monoclol | Purified | Hu |
50 µg /
€395.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA349073 | HDAC2 antibody |
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| Rabbit Polyclonal Anti-HDAC2 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| AP02667PU-N | HDAC2 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€300.00
|
||
| OriGene Technologies GmbH | |||||||
+2 additional images |
|||||||
| AP02667PU-S | HDAC2 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
50 µg /
€230.00
|
||
| OriGene Technologies GmbH | |||||||
+2 additional images |
|||||||
| AP06157PU-N | HDAC2 antibody |
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![]() |
Rabbit | Aff - Purified | Hu, Ms | E, P, WB |
0.1 mg /
€370.00
|
||
| OriGene Technologies GmbH | |||||||
+1 additional image |
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+8 additional images
















