HERC5 antibody
Principal name
HERC5 antibody
Alternative names for HERC5 antibody
E3 ISG15--protein ligase HERC5, CEB1, CEBP1, Cyclin-E-binding protein 1, HECT domain and RCC1-like domain-containing protein 5
SwissProt ID
Gene ID
51191 (HERC5)
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB)
Background of HERC5 antibody
HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
General readings
Woods MW, Kelly JN, et al. (2011). Retrovirology. 8:95. Tang Y, Zhong G, et al. (2010). J Immunol. 184(10):5777-90.
