Human IgG1 antibody
Principal name
Human IgG1 antibody
Alternative names for Human IgG1 antibody
Human Immunoglobulin G1
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Enzyme Immunoassay (E), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Immunodiffusion (ID), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of Human IgG1 antibody
IgG is a monomeric immunoglobulin composed of two heavy chains and two light chains. There are four subclasses of the IgG: IgG1, IgG2, IgG3 and IgG4. Each molecule has two antigen binding sites. IgG is the most abundant immunoglobulin as well as the only isotype that can pass through the placent,a thereby providing protection to the fetus in its first weeks of life before, its own immune system has developed. IgG can bind to several different kinds of pathogens, for example viruses, bacteria and fungi, and it protects the body against them by complement activation (the classic pathway), opsonization for phagocytosis and neutralization of their toxins.
General readings
Evaluation of monoclonal antibodies having specificity for human IgG subclasses: Results of the 2nd IUIS/WHO collaborative study. Immunology Letters 31 (1992), 143-168. Jefferis R, Reimer C B, Skavril F, de Lange G, Goodall D M, Bentley T L, Phillips D J, Vlug A, Harada S, Radl J , Claassen E, Boersma J A, and Coolen J.
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Secondary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM08151BT-N | Human IgG1 (gamma 1 chain specific) |
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Mouse | IgG1 | 4E3 | Biotin | Hu | E |
0.5 mg /
€290.00
|
| OriGene Technologies GmbH | |||||||
| AM08151FC-N | Human IgG1 (gamma 1 chain specific) |
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Mouse | IgG1 | 4E3 | FITC | Hu | ICC/IF |
0.5 mg /
€310.00
|
| OriGene Technologies GmbH | |||||||
| AM08151HR-N | Human IgG1 (gamma 1 chain specific) |
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Mouse | IgG1 | 4E3 | HRP | Hu | E |
1 ml /
€290.00
|
| OriGene Technologies GmbH | |||||||
| AM08151PU-N | Human IgG1 (gamma 1 chain specific) |
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Mouse | IgG1 | 4E3 | Purified | Hu | E, ICC/IF |
0.5 mg /
€230.00
|
| OriGene Technologies GmbH | |||||||
| AM08151RP-N | Human IgG1 (gamma 1 chain specific) |
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Mouse | IgG1 | 4E3 | PE | Hu | E, ICC/IF |
0.1 mg /
€330.00
|
| OriGene Technologies GmbH | |||||||
| AM20252BT-N | Human IgG1 (Fc specific) |
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Mouse | IgG1 | NI 132 (HP 6186) | Biotin | Hu | E, ICC/IF, IP, P, WB |
0.2 mg /
€650.00
|
| OriGene Technologies GmbH | |||||||
| AP05445PU-N | Human IgG1 |
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Sheep | IgG | Purified | Hu | E, WB |
0.5 mg /
€820.00
|
|
| OriGene Technologies GmbH | |||||||
| AP20578PU-N | Human IgG1 |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€370.00
|
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| OriGene Technologies GmbH | |||||||
 +1 additional image |
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| SM1008P | Human IgG1 (Fc specific) |
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Mouse | IgG2a | 8c/6-39 (HP6091) | Purified | Hu | C, E, ID |
0.2 mg /
€460.00
|
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| SA019 | Human IgG1 (kappa chain) |
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Human | Purified | > 95 % | Myeloma |
1 mg /
€470.00
|
| OriGene Technologies GmbH | |||||