Humanin antibody
Principal name
Humanin antibody
Alternative names for Humanin antibody
HN
SwissProt ID
Q8IVG9 (Human)
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E)
Background of Humanin antibody
Humanin is a novel 24 A.A polypeptide identified in Alzheimer's disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer's disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA336626 | Humanin antibody |
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| Rabbit Polyclonal Humanin Antibody | |||||||
![Western Blot: Humanin Antibody [TA336626] - Western blot performed from 100ng of synthetic Humanin peptide and from 50 ug of total lysates of 293 T cells transfected with plasmids encoding GFPc1 or GFP-Humanin Conditions for the Western Blot: Lysis buffer](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB300-245-1-W.jpg) |
Rabbit | Purified | Hu | WB |
0.1 ml /
€395.00
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| OriGene Technologies, Inc. | |||||||
| RA19000-100 | Humanin antibody |
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 |
Rabbit | Aff - Purified | Hu | WB |
0.1 ml /
€330.00
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| Neuromics Antibodies | |||||||