HYOU1 antibody
Principal name
HYOU1 antibody
Alternative names for HYOU1 antibody
Hypoxia up-regulated protein 1, ORP150, GRP170, ORP-150, GRP-170, 150 kDa oxygen-regulated protein, 170 kDa glucose-regulated protein
Ncbi ID
9606, 10116, NP_001124463, NP_006380, NP_001124463.1, NP_067370.3, NM_138867, BC019785, NM_006389, NM_001130991
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))
Background of HYOU1 antibody
The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses altertive transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an altertive translation initiation site, resulting in a protein that lacks the N-termil sigl peptide. This sigl peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-termil peptide sequence and to mitochondria by an amino-termil targeting sigl. Altertive splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM31092PU-N | HYOU1 antibody |
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 |
Mouse | IgG1 | 6F7 | Purified | Hu | E, P, WB |
50 µg /
€475.00
|
| OriGene Technologies GmbH | |||||||
 +2 additional images |
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| AP22660PU-N | HYOU1 (C-term) antibody |
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 |
Rabbit | Purified | Hu, Rt | E, P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
| +2 additional images |
|||||||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC214178L2V | Lenti ORF particles, HYOU1 (mGFP-tagged)-Human hypoxia up-regulated 1 (HYOU1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€2,170.00
|
|
| OriGene Technologies, Inc. | ||
| RC226294L2V | Lenti ORF particles, HYOU1 (mGFP-tagged)-Human hypoxia up-regulated 1 (HYOU1), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,170.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR208104L2V | Lenti ORF particles, Hyou1 (GFP-tagged) - Mouse hypoxia up-regulated 1 (cDNA clone MGC:30561 IMAGE:5151731), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,240.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR200176L2V | Lenti ORF particles, Hyou1 (GFP-tagged ORF) - Rat hypoxia up-regulated 1 (Hyou1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,890.00
|
|
| OriGene Technologies, Inc. | ||
| RR200176L1V | Lenti ORF particles, Hyou1 (Myc-DDK-tagged ORF) - Rat hypoxia up-regulated 1 (Hyou1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,700.00
|
|
| OriGene Technologies, Inc. | ||