INCENP antibody
Principal name
INCENP antibody
Alternative names for INCENP antibody
Inner centromere protein
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of INCENP antibody
INCENP (inner centromere protein) is one of the key components of the CPC complex (BIRC5/survivin, CDCA8/borealin, INCENP, AURKB and AURKC) which implicates in the regulation of mitotic cell division. CPC complex play a critical role at centromeres in facilitating correct chromosome alignment/segregation and is essential for chromatin-induced microtubule stabilization as well as spindle assembly. INCENP has been shown to localize to inner kinetochore and on chromosome arms and inner centromeres from prophase through metaphase and then transferring to spindle midzone and midbody from aphase through cytokinesis. INCENP exists as a homodimer or heterodimer, interacts with several proteins that includes H2AFZ, CBX3, tubulin beta chain, AURKB/AURKC, EVI5, CDCA8, BIRC5, CBX5; CBX5, POGZ, and JTB. Moreover, INCENP colocalizes with AURKB at mitotic chromosomes where INCENP-AURKB/AURKC association is important for its functions and INCENP also binds directly to microtubules for regulating the kinetochore localization of BUB1.
- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA336285 | INCENP antibody |
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| Rabbit Polyclonal INCENP Antibody | |||||||
![Western Blot: INCENP Antibody [TA336285] - Western blot analysis of HeLa (1), A431 (2), MCF7 (3), HEK293 (4), Neuro2a (5), and Raw 264.7 (6) cell lysate using INCENP antibody at a concentration of 2 ug/ml.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB100-2286-1-W.jpg) |
Rabbit | Purified | Hu | ICC/IF, WB |
0.1 ml /
€395.00
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| OriGene Technologies, Inc. | |||||||
 +4 additional images |
Highly validated antibody! |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY420743 | INCENP overexpression lysate |
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0.1 mg /
€495.00
|
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| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR211041L2V | Lenti ORF particles, Incenp (GFP-tagged) - Mouse inner centromere protein (Incenp), 200 uL, >10^7 TU/mL |
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200 µl /
€1,710.00
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| OriGene Technologies, Inc. | ||
| MR211041L1V | Lenti ORF particles, Incenp (Myc-DDK-tagged) - Mouse inner centromere protein (Incenp), 200 uL, >10^7 TU/mL |
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200 µl /
€1,540.00
|
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| OriGene Technologies, Inc. | ||
