INPPL1 antibody
Principal name
INPPL1 antibody
Alternative names for INPPL1 antibody
INPPL-1, SHIP2, SHIP-2, Inositol polyphosphate phosphatase-like protein 1, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2, SH2 domain-containing inositol-5'-phosphatase 2
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P)
Background of INPPL1 antibody
INPPL1 (Inositol polyphosphate phosphatase-like 1), also called SHIP2, encodes inositol polyphosphate-5 phosphatase-like 1, a protein that in addition to the phosphatase domain contains an SH2 (src-homology domain 2) motif. INPPL1 is a member of the family of inositol triphosphate phosphatases. The INPPL1 gene is mapped on 11q13.4. Immunoblot analysis revealed that SHIP2 was widely expressed in fibroblast and nonhematopoietic tumor cell lines, unlike the SHIP protein, which was found only in cell lines of hematopoietic origin. Using human epithelial cell lines and primary human corneal and epidermal keratinocytes, Yu et al. (2008) showed that microRNA-184 (MIR184) interfered with the ability of MIR205 to downregulate expression of SHIP2.SHIP2 may play a significant role in regulation of phosphatidylinositol 3-prime-kinase signaling by growth factors and insulin. By targeting the translation-initiating ATG codon and deleting the first 18 exons encoding Inppl1, Sleeman et al. (2005) generated Inppl1 -/- mice that were null for Inppl1 mRNA and protein.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| RA18031-100 | INPPL1 antibody |
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Rabbit | Aff - Purified | Hu, Rt | F, ICC/IF, IP, WB |
0.1 ml /
€420.00
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| Neuromics Antibodies | |||||||
 +2 additional images |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY419859 | INPPL1 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
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| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC214716L1V | Lenti ORF particles, INPPL1 (Myc-DDK-tagged)-Human inositol polyphosphate phosphatase-like 1 (INPPL1), 200 uL, >10^7 TU/mL |
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|
200 µl /
€1,250.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR211861L2V | Lenti ORF particles, Inppl1 (GFP-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,250.00
|
|
| OriGene Technologies, Inc. | ||
| MR211861L1V | Lenti ORF particles, Inppl1 (Myc-DDK-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,030.00
|
|
| OriGene Technologies, Inc. | ||