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KCNA2 antibody

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Principal name

KCNA2 antibody

Alternative names for KCNA2 antibody

Potassium voltage-gated channel subfamily A member 2, Voltage-gated potassium channel subunit Kv1.2, HBK5, NGK1, HUKIV, KCNA2

SwissProt ID

P16389 (Human), P22739 (Xenla), P63141 (Mouse), P63142 (Rat), Q09081 (Rabit), Q28293 (Canfa)

Gene ID

3737 (KCNA2), 16490 (Kcna2), 25468

Ncbi ID

NP_004965.1, 10090, 10116, NP_032443.3, NP_004965, AAH43564.1, NP_037102.1, NM_008417, NM_012970, NM_004974

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Xen (Xenopus), Ze (Zebrafish), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of KCNA2 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alpha- subunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1-KV4 subfamilies generate functional K+ channels in a homotetrameric configuration (3).

General readings

Denning, E.J., et al. Mol. Membr. Biol. 26(8):397-421(2009)
Peters, C.J., et al. Channels (Austin) 3(5):314-322(2009)
Martos, V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(26):10482-10486(2009)
Stirling, L., et al. Mol. Biol. Cell 20(12):2991-3002(2009)
Zhu, J., et al. Biochem. J. 375 (PT 3), 769-775 (2003)

AP52299PU-N - KCNA2
Immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue reacted with AP52299PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining.
AP52299PU-N - KCNA2
Western blot analysis of KCNA2 Antibody (C-term) Cat.-No AP52299PU-N in CEM cell line lysates (35ug/lane). This demonstrates the KCNA2 antibody detected the KCNA2 protein (arrow).
MO50016-100 - KCNA2
Kv1.2 western blots of membranes from whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].
MO50016-100 - KCNA2
 Kv1.2 staining of adult rat hippocampus. 
TP322200 - KCNA2
75-008 - KCNA2
adult rat brain membrane immunoblot.
75-008 - KCNA2
immunoblot on brain membranes from wild-type (WT) and Kv1.2 knockout (Kv1.2-/-) mice and from adult rat brain (RBM).
75-008 - KCNA2
adult rat hippocampus immunohistochemistry
75-008 - KCNA2
immunoblot on membranes from whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].
73-008 - KCNA2
adult rat brain membrane immunoblot.
73-008 - KCNA2
immunoblot on brain membranes from wild-type (WT) and Kv1.2 knockout (Kv1.2-/-) mice and from adult rat brain (RBM).
73-008 - KCNA2
adult rat hippocampus immunohistochemistry
73-008 - KCNA2
immunoblot on membranes from whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].
73-314 - KCNA2
Adult rat brain membrane immunoblot
75-314 - KCNA2
Adult rat brain membrane immunoblot
TA309706 - KCNA2
Western Blot: Kv1.2 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv1.2 (lanes 2 and 4) and transfected with Kv1.3 (lane 3) were subjected to 10% SDS-PAGE and were Western blotted with the Kv1.2 Antibody . Lane 4 was probed with anti-Kv 1.2 that had been preincubated with the peptide used to generate the antibody.
TA309707 - KCNA2
Immunocytochemistry: Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells using anti-Kv 1.2. Nuclei (Blue) are counterstained using Hoechst 33258.
TA326482 - KCNA2
IHC analysis of Kv1.2 in frozen sections of mouse brain extract using the antibody
TA328929 - KCNA2
Western blot analysis of rat brain membranes: 1. Anti-KV1.2 antibody , (1:200). 2. Anti-KV1.2 antibody, preincubated with the control peptide antigen.
TA328929 - KCNA2
Western blot analysis of rat heart membranes: 1. Anti-KV1.2 antibody , (1:200) 2. Anti-KV1.2 antibody, preincubated with the control antigen.
TA336756 - KCNA2
Western Blot: Kv1 Antibody [TA336756] - Membrane preparations from HEK-293 cells untransfected (lane 1) transfected with Kv1.2 (lanes 2 and 4) and transfected with Kv1.3 (lane 3) were subjected to 10% SDS-PAGE and were Western blotted with Kv1 Antibody (T
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  2. Highly Validated (2)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNA2 antibody
adult rat brain membrane immunoblot. Mouse IgG2b K14/16 Supernatant Hu, Ms, Rt, Xen, Ze C, ICC/IF, IP, WB
5 ml / €490.00
  Antibodies Incorporated
+3 additional images

Highly validated antibody!

NeuroMab

KCNA2 antibody
adult rat brain membrane immunoblot. Mouse IgG2b K14/16 Purified Hu, Ms, Rt, Xen, Ze C, ICC/IF, IP, WB
0.1 ml / €570.00
  Antibodies Incorporated
+3 additional images

Highly validated antibody!

NeuroMab

KCNA2 antibody
  Rabbit Polyclonal Kv1.2 Antibody  
Western Blot: Kv1.2 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv1.2 (lanes 2 and 4) and transfected with Kv1.3 (lane 3) were subjected to 10% SDS-PAGE and were Western blotted with the Kv1.2 Antibody . Lane 4 was probed with anti-Kv 1.2 that had been preincubated with the peptide used to generate the antibody. Rabbit Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Xen IP, WB
0.1 ml / €415.00
  OriGene Technologies, Inc.

KCNA2 antibody
  Rabbit Polyclonal Kv1.2 Antibody  
Immunocytochemistry: Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells using anti-Kv 1.2. Nuclei (Blue) are counterstained using Hoechst 33258. Rabbit Purified Bov, Can, Hu, Ms, Por, Rt, Xen, Ze ICC/IF, WB
0.1 ml / €395.00
  OriGene Technologies, Inc.

KCNA2 antibody
  Mouse Monoclonal Anti-Kv1.2 Antibody  
IHC analysis of Kv1.2 in frozen sections of mouse brain extract using the antibody Mouse IgG2b S14-16 Purified Hu, Ms, Rt, Xen, Ze C, ICC/IF, WB
0.1 mg / €410.00
  OriGene Technologies, Inc.

KCNA2 antibody
  Rabbit polyclonal Anti-KV1.2  
Western blot analysis of rat brain membranes: 1. Anti-KV1.2 antibody , (1:200). 2. Anti-KV1.2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+1 additional image

KCNA2 antibody
  Rabbit Polyclonal Kv1 Antibody  
Western Blot: Kv1 Antibody [TA336756] - Membrane preparations from HEK-293 cells untransfected (lane 1) transfected with Kv1.2 (lanes 2 and 4) and transfected with Kv1.3 (lane 3) were subjected to 10% SDS-PAGE and were Western blotted with Kv1 Antibody (T Rabbit Purified Bov, Can, Hu, Ms, Por, Rt IP, WB
0.1 ml / €395.00
  OriGene Technologies, Inc.

KCNA2 antibody
Adult rat brain membrane immunoblot Mouse IgG2a L76/36 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €490.00
  Antibodies Incorporated
 

NeuroMab

KCNA2 antibody
Adult rat brain membrane immunoblot Mouse IgG2a L76/36 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €570.00
  Antibodies Incorporated
 

NeuroMab

KCNA2 antibody
KCNA2 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €400.00
  OriGene Technologies GmbH

KCNA2 (C-term) antibody
Immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue reacted with AP52299PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

KCNA2 antibody
KCNA2 Rabbit Purified Hu C, E, WB
0.1 mg / €450.00
  OriGene Technologies GmbH

KCNA2 antibody
Kv1.2 staining of adult rat hippocampus. Mouse IgG2a Aff - Purified Hu, Ms, Rt, Xen, Ze C, ICC/IF, IP, WB
0.1 ml / €440.00
  Neuromics Antibodies
+3 additional images

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KCNA2
  Recombinant protein of human potassium voltage-gated channel, shaker-related subfamily, member 2 (KCNA2)  
KCNA2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcna2 (GFP-tagged) - Mouse potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcna2 (GFP-tagged) - Mouse potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Kcna2 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcna2 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcna2 (GFP-tagged ORF) - Rat potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcna2 (GFP-tagged ORF) - Rat potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Kcna2 (Myc-DDK-tagged ORF) - Rat potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Kcna2 (Myc-DDK-tagged ORF) - Rat potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.
 

18 Item(s)

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18 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (2)
  2. Primary Antibody (13)
  3. Protein | Growth Factor (1)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (7)
  2. Monoclonal (6)
Target
  1. KCNA2 (14)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (13)
  2. Mouse (Ms) (11)
  3. Rat (Rt) (11)
  4. Xenopus (Xen) (6)
  5. Zebrafish (Ze) (5)
  6. Bovine (Bov) (3)
  7. Canine (Can) (3)
  8. Porcine (Por) (3)
  9. Rabbit (Rb) (1)
Applications
  1. Western blot / Immunoblot (WB) (13)
  2. Frozen sections (C) (7)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (7)
  4. Immunoprecipitation (IP) (5)
  5. Enzyme Immunoassay (E) (1)
  6. Paraffin Sections (P) (1)
Presentation
  1. Purified (9)
  2. Aff - Purified (2)
  3. Supernatant (2)
Host
  1. Rabbit (7)
  2. Mouse (6)
Images
  1. 1 image (12)
  2. 3+ images (3)
Images: Applications
  1. Western blot / Immunoblot (WB) (9)
  2. Frozen sections (C) (2)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
  5. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (13)
  2. Antibodies Incorporated (4)
  3. Neuromics Antibodies (1)
Service
  • OriGene Technologies GmbH
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