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KCNH7 antibody

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Principal name

KCNH7 antibody

Alternative names for KCNH7 antibody

KCNH7, ERG3, HERG-3, Ether-a-go-go-related protein 3, Eag-related protein 3, Potassium voltage-gated channel subfamily H member 7, Voltage-gated potassium channel subunit Kv11.3, Ether-a-go-go-related gene potassium channel 3

SwissProt ID

O54852 (Rat), Q9ER47 (Mouse), Q9NS40 (Human)

Gene ID

90134 (KCNH7), 170739 (Kcnh7)

Ncbi ID

9606, NP_775185, NP_150375, NM_033272, NP_571987.1, NP_150375.2, NM_173162

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of KCNH7 antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH7 is a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.

General readings

Alkelai,A., et.al., Psychopharmacology (Berl.) 206 (3), 491-499 (2009)
Couturier,N., et.al., Eur. J. Hum. Genet. 17 (6), 844-847 (2009)

ARP35484_P050 - KCNH7
Human 721_B; WB Suggested Anti-KCNH7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 721_B cell lysate; KCNH7 antibody - N-terminal region (ARP35484_P050) in Human 721_B cells using Western Blot
ARP35379_P050 - KCNH7
Human Small Intestine; WB Suggested Anti-KCNH7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Small Intestine; KCNH7 antibody - middle region (ARP35379_P050) in Human Small Intestine cells using Western Blot
AP52306PU-N - KCNH7
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCNH7 Antibody (N-term) Cat.-No AP52306PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
AP52306PU-N - KCNH7
Western blot analysis of KCNH7 Antibody (N-term) Cat.-No AP52306PU-N in T47D cell line lysates (35ug/lane). KCNH7 (arrow) was detected using the purified Pab.
AP52306PU-N - KCNH7
Flow cytometric analysis of HepG2 cells using KCNH7 Antibody (N-term) Cat.-No AP52306PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
TA328969 - KCNH7
Western blot analysis of rat brain lysate: 1. Anti- Kv11.3 (erg3) antibody , (1:300). 2. Anti- Kv11.3 (erg3) antibody, preincubated with the control peptide antigen.
TA328969 - KCNH7
Expression of KV11.3 in rat cerebellum. Immunohistochemical staining of rat cerebellum using Anti-Kv11.3 (erg3) antibody . A. Kv11.3 channel appears in glial processes (red). B. Staining of astrocytic fibers with mouse anti glial fibrillary acidic protein (GFAP, green). C. Confocal merge of Kv11.3 channel and GFAP demonstrates colocalization in the molecular layer but separate localization of these proteins at the Purkinje cell layer.
TA338722 - KCNH7
WB Suggested Anti-KCNH7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Small Intestine
TA338765 - KCNH7
WB Suggested Anti-KCNH7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate
CPA9412-100ul - KCNH7
Western blot analysis of Kv11.3 expression in HeLa (A); mouse brain (B); rat brain (C) whole cell lysates.
CPA9412-100ul - KCNH7
Immunohistochemical analysis of Kv11.3 staining in rat brain;mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNH7 antibody
  Rabbit polyclonal Anti-KV11.3 (erg3)  
Western blot analysis of rat brain lysate: 1. Anti- Kv11.3 (erg3) antibody , (1:300). 2. Anti- Kv11.3 (erg3) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+1 additional image

KCNH7 (N-term) antibody
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCNH7 Antibody (N-term) Cat.-No AP52306PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+2 additional images

Lysates

Catalog No.    

KCNH7 overexpression lysate
KCNH7 overexpression lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNH7 (mGFP-tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 7 (KCNH7), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, KCNH7 (mGFP-tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 7 (KCNH7), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,490.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, KCNH7 (Myc-DDK tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 7 (KCNH7), transcript variant 1 , 200 uL, >10^7 TU/mL
Lenti ORF particles, KCNH7 (Myc-DDK tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 7 (KCNH7), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €2,250.00
  OriGene Technologies, Inc.
 

5 Item(s)

per page

Available Filters

Product Type
  1. Human Lenti ORF Particle (2)
  2. Lysate (1)
  3. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. KCNH7 (2)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (1)
  3. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Flow cytometry (F) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Flow cytometry (F) (1)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (5)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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