KIF5A antibody
Principal name
KIF5A antibody
Alternative names for KIF5A antibody
KIF5A, NKHC1, Kinesin heavy chain isoform 5A, Neuronal kinesin heavy chain, NKHC, Kinesin heavy chain neuron-specific 1
Ncbi ID
NP_004975, 9606, NP_004975.2, Q12840, NM_008447, NM_212523, NP_001034089.1
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of KIF5A antibody
Kinesins are microtubule-based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains.
Kinesin heavy chain isoform 5A is a neuron-specific member of the kinesin 5 (Kif5) family, consisting of the heavy chains of conventional kinesins. Mutation in human homolog causes autosomal dominant spastic paraplegia 10.
Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain.
There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.
General readings
Reid,E., et al., (2002) Am. J. Hum. Genet. 71 (5), 1189-1194
- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP08937PU-N | KIF5A antibody |
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
50 µg /
€425.00
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| OriGene Technologies GmbH | |||||||
 +3 additional images |
Highly validated antibody! |
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| TA306456 | KIF5A (C-term) antibody |
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| Rabbit Polyclonal KIF5 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
| +2 additional images |
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| TA306457 | KIF5A (Center) antibody |
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| Rabbit Polyclonal KIF5 Antibody | |||||||
 |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
| +2 additional images |
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Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR211477L2V | Lenti ORF particles, Kif5a (GFP-tagged) - Mouse kinesin family member 5A (Kif5a), transcript variant 2, 200 uL, >10^7 TU/mL |
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200 µl /
€1,920.00
|
|
| OriGene Technologies, Inc. | ||
| MR211477L1V | Lenti ORF particles, Kif5a (Myc-DDK-tagged) - Mouse kinesin family member 5A (Kif5a), transcript variant 2, 200 uL, >10^7 TU/mL |
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|
200 µl /
€1,730.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR205902L2V | Lenti ORF particles, Kif5a (GFP-tagged ORF) - Rat kinesin family member 5A (Kif5a), 200 uL, >10^7 TU/mL |
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200 µl /
€2,280.00
|
|
| OriGene Technologies, Inc. | ||
| RR205902L1V | Lenti ORF particles, Kif5a (Myc-DDK-tagged ORF) - Rat kinesin family member 5A (Kif5a), 200 uL, >10^7 TU/mL |
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|
200 µl /
€2,060.00
|
|
| OriGene Technologies, Inc. | ||