LALBA antibody

Principal name

LALBA antibody

Alternative names for LALBA antibody

LALBA, LYZL7, Alpha-lactalbumin, Lactose synthase B protein, Lysozyme-like protein 7

SwissProt ID

P00709 (Human), P00711 (Bovin)

Gene ID

3906 (LALBA)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunodiffusion (ID)

Background of LALBA antibody

LALBA(lactalbumin, alpha or alpha-lactalbumin) is a protein that in humans is encoded by the LALBA gene. The LALBA gene is mapped on 12q13.11. alpha-Lactalbumin is an important whey protein in cow's milk (~1 g/l), and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. alpha-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta-1, 4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a multimer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of human alpha-lactalbumin that may form in acidic environments such as the stomach, called HAMLET, probably induces apoptosis in tumor and immature cells.

General readings

Tolin, S., et al. FEBS J. 277(1):163-173 (2010)
Rosner, H.I., et al. J. Mol. Biol. 394(2):351-362 (2009)
Wang, J., et al. J. Dairy Sci. 91(12):4466-4476 (2008)
Ramboarina, S., et al. J. Am. Chem. Soc. 130(46):15318-15326 (2008)
Morozova, O.B., et al. J Phys Chem B 109(12):5912-5918 (2005)

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LALBA (Center) antibody

Western blot analysis in CEM cell line lysates (35ug/lane) using LALBA antibody Cat.-No. AP52439PU-N. This demonstrates the LALBA antibody detected the LALBA protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LALBA

  Recombinant protein of human lactalbumin, alpha- (LALBA)  
LALBA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

2 Item(s)

per page
  • LinkedIn