Lipid A antibody
Principal name
Lipid A antibody
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Agglutination (AGG)
Background of Lipid A antibody
Lipid A is part of a Gram-negative bacterial endotoxin located at one end of the lipopolysaccharide (LPS) molecule. Lipid A is made up of two glucosamine units with attached acyl chains, and it usually contains one phosphate group on each carbohydrate. Lipid A functions to anchor the LPS to the outer membrane of a Gram-negative bacteria. The toxicity of Gram-negative bacteria is due to Lipid A since this is what the human immune system recognizes, though this recognition is also critical for the onset of immune responses to Gram-negative infection and for the subsequent successful fight against the infection. Lipid A may play a role in to activating cells via Toll-like receptor 4 (TLR4), MD-2, and CD14 on the cell surface. When present in the body at high concentrations during a Gram-negative bacterial infection, Lipid A can cause shock and death because it is such a potent immune system activator.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM26275LE-N | Lipid A (free) antibody |
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Mouse | IgM | 43 | Low Endotoxin | E, WB |
0.2 mg /
€450.00
|
|
| OriGene Technologies GmbH | |||||||
| AM32312SU-N | Lipid A antibody |
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|
Mouse | IgG2b | 26-5 | Purified | AGG, E |
1 ml /
€260.00
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|
| OriGene Technologies GmbH | |||||||