LMO4 antibody
Principal name
LMO4 antibody
Alternative names for LMO4 antibody
LMO4, LIM domain transcription factor LMO4, LIM domain only protein 4, LMO-4, Breast tumor autoantigen
Ncbi ID
9606, NP_006760, NP_006760.1, NM_006769, NP_001155241.1, NM_010723, NM_001161769, NM_001161770
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)
Background of LMO4 antibody
The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.
General readings
Tian, Y., et al. Clin. Exp. Metastasis 27(7):455-463(2010)
Ribases, M., et al. Biol. Psychiatry 66(10):926-934(2009)
Montanez-Wiscovich, M.E., et al. Oncogene 28(41):3608-3618(2009)
Huang, Z., et al. Dev. Biol. 327(1):132-142(2009)
Caporaso, N., et al. PLoS ONE 4 (2), E4653 (2009)
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Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA314767 | LMO4 antibody |
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| Rabbit polyclonal anti-LMO4 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
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| OriGene Technologies, Inc. | |||||||
| TA324369 | LMO4 (Center) antibody |
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| Rabbit polyclonal LMO4 Antibody (Center) | |||||||
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Rabbit | Ig | Aff - Purified | Hu, Ms | F, WB |
0.4 ml /
€415.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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| AM20959PU-N | LMO4 antibody |
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Mouse | IgG2b | 2B6 | Hu | E, P |
50 µg /
€475.00
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| OriGene Technologies GmbH | |||||||
| AP20393PU-N | LMO4 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€370.00
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| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303914 | LMO4 |
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| Recombinant protein of human LIM domain only 4 (LMO4) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
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|
| OriGene Technologies, Inc. | |||||
Published recently! |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY402024 | LMO4 overexpression lysate |
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0.1 mg /
€295.00
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|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR201329L2V | Lenti ORF particles, Lmo4 (GFP-tagged) - Mouse LIM domain only 4 (Lmo4), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€930.00
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| OriGene Technologies, Inc. | ||
| MR201329L1V | Lenti ORF particles, Lmo4 (Myc-DDK-tagged) - Mouse LIM domain only 4 (Lmo4), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€830.00
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| OriGene Technologies, Inc. | ||